Jagotec Ag

Ekita Investments N.v.

Laboratorio Farmaceutico C.t. S.r.l.

Pharmidea

Aldo La Manna

Ubaldo Conte

Lauretta Maggi

Paolo Colombo

Paolo Giunchedi

Giuseppe Tessitore

A process is described for preparing pharmaceutical compositions by co-grinding or dry mixing the active substance with cyclodextrins or with hydrophilic polymer materials which swell on contact with water. Homogeneous compositions are obtained from which the active substance is released very rapidly into an aqueous medium.

Process for preparing pharmaceutical composition having an increased

Pharmaceutical tablet capable of liberating one or more drugs at

A pharmaceutical tablet capable of releasing the active ingredients contained therein at subsequent times produced via the steps of: a) preparing a tablet consisting of three superposed layers, the upper layer containing an active ingredient, the intermediate layer not containing any active ingredient and forming a barrier-type layer, and the lower layer containing an active ingredient, said upper layer presenting a raised top, b) coating the tablet entirely with an impermeable polymeric film, and c) removing said raised top and thus allowing contact of the abraded upper layer surface with the environment.

Pharmaceutical tablet capable of releasing the active ingredients

Controlled release pharmaceutical tablet having a lenticular form consisting of three layers of which the central one or core (a) contains the active principle and the two outer layers or barriers (b) and (c) comprise gellable and/or erodible polymeric material, said barrier layers being equal or different among themselves for composition and/or thickness, while the central layer has a limited external annular surface exposed to the dissolution medium, through which the active principle is released.

Controlled release pharmaceutical tablet having lenticular form

Controlled release pharmaceutical compositions administrable by oral route, containing as the active principle at least one salt of the gamma hydroxy butyric acid with a pharmaceutically acceptable cation, for the treatment of alcoholism, opium like substances addiction, heroin addiction, food and nicotine addiction, depressive and anxious states, composed by:

Controlled release pharmaceutical compositions based on one or more

Process for preparing pharmaceutical tablet capable of releasing the

Process for preparing pharmaceutical compositions having an increased

Pharmaceutical tablets releasing the active substance after a definite period of time, consisting of: a core containing the active substance and polymeric substances which swell and/or gel and/or erode on contact with water or with aqueous liquids; a layer applied externally to said core, suitable to prevent the immediate release of the active substance contained in the core and to allow the release of said active substance after a definite period of time, consisting of natural and/or synthetic polymeric materials of the class of the hydrophilic polymers which erode and/or gel and/or dissolve in an aqueous medium; a possible gastroresistant and enterosoluble coating.

Pharmaceutical tablets releasing the active substance after a definite

Tablets with zero order controlled-rate of release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on contact with aqueous liquids and polymer substances with gelling properties, and a support applied to said core to partly cover its surface, the support consisting of polymer substances which are slowly soluble and/or slowly gellable in aqueous liquids, plasticizing substances, and possibly substances with an adjuvant function.

Tablets with controlled-rate release of active substances

A tablet for pharmaceutical use able to release active substances at successive times, comprising at least; a first layer containing a portion of the active substance with suitable excipients, a barrier layer of polymer material gellable and/or soluble in water and/or aqueous liquids, which is interposed between said first layer and a third layer containing the remaining portion of active substance with suitable excipients, said barrier layer and said third layer being housed in a casing consisting of polymer material impermeable and insoluble in water or soluble in an alkaline environment. That part of the active substance not inserted in the casing is immediately available for dissolving, whereas the part inserted in the casing is available only after dissolution or rupture of the barrier layer and/or after solubilization of the casing.

Tablet for pharmaceutical use able to release active substances at

A system for the controlled-rate release of active substances, consisting of:

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Pavia, Italy

Aldo La Manna