Archimica S.r.l.

Italfarmaco Spa

Clariant Life Science Molecules (italia) S.p.a.

Clariant Lsm Italia S.p.a.

Aldo Banfi

Alfredo Mancini

Marco Frigerio

Francesca Benedini

Alberto Sala

Roberta Cereda

Bruno Dall'Oro

Pietro Bellani

Gianluca Di Lernia

Deborah Bollini

Maurizio Serra

Process for preparing oxcarbazepine according to the steps of chlorocarbonylating (a), ammonolysis (b), and deprotecting (c).  The invention is characterized by the use of triphosgene as chlorocarbonylating agent in step a).

Process for preparing oxcarbazepine

A process for the preparation of ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid. Said process comprises:   

Process for the preparation of D-ribavirin

A process for the preparation of L-ribavirin on an industrial scale is described which comprises the reaction of glycosylation of 3-substituted triazoles in the presence of a Lewis acid. Said process comprises:   

Process for the preparation of L-ribavirin

A process is disclosed for manufacturing N-methyl-N-phenylaminoacrolein of formula (I) which comprises reacting N-methylformanilide and an alkyl vinyl ether of formula (III) wherein R is a C&#x2013;Calkyl, said process being characterized in that the reaction between N-methylformanilide and said alkyl vinyl ether of formula (III) is carried out in the presence of phosgene, diphosgene or triphosgene in a solvent selected from dioxane, acetonitrile and/or chlorobenzene.

Synthesis of N-methyl-N-phenylaminoacrolein

Process for the preparation of (S)-N-tert-butyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide

##STR1## Compounds of formula (I) wherein X, Y, R.sub.1 and R.sub.2 have the meanings specified in the specification, are endowed with cardiovascular activity.

Benzoic acid substituted derivatives having cardiovascular activity

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Milan, Italy

Aldo Banfi