Politecnico Di Milano

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Fondazione Istituto Italiano Di Tecnologia

UniversitÁ Degli Studi Di Genova

Vermon S.a.

Micro Photon Devices Srl

Alberto Tosi

Franco Zappa

Alberto Diaspro

Paolo Bianchini

Federica Villa

Giuseppe Vicidomini

Paola Taroni

Bogdan Rosinski

Marco Castello

Jean-Marc Dinten

Alberto Dalla Mora

Mauro Buttafava

Simone Tisa

Colin J R Sheppard

Antonio Pifferi

Emmanuel Montauban

Alessandro Ruggeri

Giorgio Tortarolo

Alessandro Torricelli

Davide Contini

Antonio Giovanni Pifferi

Laura Di Sieno

Enrico Conca

Gabriele Scrofani

Federica Alberta Villa

A portable two-mode probe to be applied against a biological tissue to be examined, the probe including an ultrasonic transducer configured to emit ultrasonic waves into the tissue and to receive ultrasonic waves reflected by the tissue, the transducer extending along a transverse axis; and at least two optodes placed on either side of the transverse axis, such that the transducer extends between the two optodes. Further, each optode includes a casing containing a light emitter configured to emit a light wave toward the tissue, and/or an optical detector configured to detect a light wave scattered by the tissue. The optodes are arranged such that at least one light emitter and at least one optical detector are placed on either side of the transducer, and at least one optical detector has a detection area formed from a semiconductor and connected to a circuit board.

Bimodal ultrasonic probe comprising an optical device for diagnosis

A method for operating a point laser-scanning microscope includes scanning a sample with a focused illumination laser beam; recording a plurality of images by detecting elements being configurable to an intensity mode, in which the recorded images are intensity images g(n) related to photons collected during an entire dwell time of the illumination beam on an individual position n, or to a time-resolved mode, in which the recorded images are time-resolved images g(n, t), the collected photons being discriminated based on their arrival times to individual detecting elements; calculating a fingerprint image a by summing the plurality of intensity images g(n) over all positions n; estimating shift matrices sand sfrom the intensity images g(n); reconstructing at least one of a time-resolved object function fand an intensity object function f; and visualizing at least one of a high-resolution time-resolved image fand a high-resolution intensity image f.

Time-resolved imaging method with high spatial resolution

Growing community of inventors

Paruzzaro, Italy

Alberto Tosi