Consejo Superior De Investigaciones Cientificas

Palau Pharma, S.a.

Universidad Complutense De Madrid

J. Uriach & Cia, S.a.

Alberto Gallardo Ruiz

Juan Rodríguez Hernández

Carlos Elvira Pujalte

Helmut Reinecke

Gema Rodriguez Crespo

Carolina García Sánchez

Julio San Román Del Barrio

Ana Civantos Fernández

Julio San-Román Del Barrio

Gema Rodríguez Crespo

Maria Eugenia Pérez Ojeda

Mar Fernández Gutiérrez

Enríque Martínez Campos

Luis Duocastella Codina

Enrique Martínez Campos

Maria Molina Crisol

Ana María Santos Coquillat

María Eugenia PÉREZ Ojeda

The invention relates to a hydrogel based on vinyl caprolactam, with or without additional monomers, and at least two crosslinkers. The invention also relates to a method for obtaining said material and to the use thereof to culture cells/engineer cell monolayers, as well as supports for cell culture and transplant.

Hydrogels based on vinyl-caprolactam

The invention relates to a material formed by a polymer substrate and a hydrogel based on vinyl-lactams and ionic methacrylates. The invention also relates to a method for producing this material and to the use thereof for cell culture and cell monolayer engineering, for preparing 3D scaffolds and manufacturing thermosensitive mechanical actuators.

Vinyl-lactam-based hydrogel coatings

New triflusal-containing polymeric compounds resulting from the polymerization of 2-(methacryloyloxy)ethyl 2-acetyloxy-4-(trifluoromethyl)benzoate with butyl acrylate are described. These new polymers exhibit good adhesion and crack-bridging properties and are particularly suitable for the coating of stents.

Triflusal-containing polymers for stent coating

New biocompatible polymeric systems carrying triflusal or HTB are described which result from the polymerization of a monomer A of the acrylic or vinylic type and carrying triflusal or HTB, wherein triflusal or HTB are linked to the remainder of the molecule of said monomer through an in vivo hydrolysable covalent bond, and optionally a second polymerisable monomer B. These new polymeric systems are useful as coating for synthetic biomaterials.

Biocompatible polymeric systems carrying triflusal or HTB

Biocompatible polymer systems carrying triflusal or HTB

Growing community of inventors

Madrid, Spain

Alberto Gallardo Ruiz