Bioman S.r.l.

Gnosis Spa

Gnosis Srl

Alberto Benedetti

Francesco Girardo

Hermes Pagani

Matilde Manzoni

Simona Daly

Enrica Canzi

Salvatore Ciappellano

Lino Sivieri

Michela Fumagalli

Manuela Silvia Rollini

Enrico Giuseppe Roberto Berardi

Marina Nichele

Roberto Xaiz

Manuela Rollini

Vincenzina Andreoni

The invention relates to a zinc-enriched biomass comprising living or subsequently killed micro-organisms, selected from the group consisting ofandsubsp.and combinations thereof, a method for the manufacture of said zinc-enriched biomass, as well as food preparations, nutraceutic products, functional foods, cosmetic and cosmeceutic products, and food supplements, comprising the said biomass. Furthermore, new micro-organism strains are described which are able to concentrate zinc within the cell in very high amounts and therefore are particularly suitable for use in the method of the invention.

Zinc-enriched biomass, method for the preparation thereof and pro-biotic, cosmetic, dietary and nutraceutic products comprising the same

Disclosed are dried and/or microencapsulatedcells with a high content of (S)-(+)-S-adenosyl-L-methionine, in the form of a free base obtainable from selected high-productivity strains of (S)-(+)-SAMe.

[object Object]

The invention relates to a method for the preparation of a copper-enriched biomass, comprising, in a first step, culturingyeast cells in a liquid nutrient medium comprising a carbon source, a nitrogen source, at least one amino acid and a copper salt, so as to obtain copper-enriched yeast biomass in the form of a Cu-GSH complex, wherein the intracellular content of Cu-GSH is higher than 1% dw and, in a second step, separating the copper-enriched yeast biomass from the nutrient liquid medium. Two strains ofare described, designated as SA 221 BM and SA 586 BM, respectively (accession numbers DSM 21530 and DSM 21531, deposited with the DSMZ on Jun. 6, 2008), which have the ability to accumulate particularly high levels of intracellular copper. Moreover, the invention relates to the copper-enriched yeast biomass obtainable by the method of the invention, which has an intracellular Cu-GSH content higher than 1% dw, and its use in cosmetic and probiotic products.

Copper-enriched biomass, method for the preparation thereof and pro-biotic, cosmetic, dietary and nutraceutic products comprising the same

A process for the preparation of vitamin K2 (MK-7) comprising the culture ofmutant strain GN13/72-DSM 17766 deposited on Dec. 5, 2005 at the DSMZ.

Process for the preparation of vitamin K2

The invention relates to a selenium-enriched biomass containing live microorganisms selected from the group consisting ofand combinations thereof, a method of preparation of the said selenium-enriched biomass, as well as food preparations, nutraceutical products and food supplements containing the said biomass. Moreover, new strains of lactobacilli are described that are able to concentrate selenium in very high amounts, and are therefore particularly useful for use in the method of the invention.

Selenium-enriched biomass, method for preparing thereof and probiotic and nutraceutical products including said biomass

There is disclosed a fermentation process for producing glutathione which comprises (a) the obtainment of a biomass pre-culture by pre-cultivating, in aerobic conditions, a strain of a glutathione producing yeast wherein the glutathione content per biomass unit is higher than 1.2% w/w; (b) the cultivation, in aerobic conditions, of the resulting biomass pre-culture such that the resulting biomass density is higher than 50 g/l; (c) the activation of the cultured biomass; and (d) the recovery of the cultured biomass, extracting glutathione at a pH equal to or lower than 6 and purifying the resulting glutathione. The process allows to obtain glutathione with high yields and relatively low costs.

Process for producing glutathione

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Cernusco sul Naviglio, Italy

Alberto Benedetti