Roche Diagnostics Operations, Inc.

Roche Diagnositcs Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Albert Roeder

Carlo S Effenhauser

Manfred Watzele

Remo Anton Hochstrasser

Alois Rainer

Peter Berndt

Bernd Buchberger

Hanno Langen

Wolfgang Mutter

Hans-Joachim Hoeltke

Stephanie Wessner

Cordula Jany

A separation device and a separation method for biomolecular sample material and in particular protein mixtures. For this purpose a separation elementfor the two-dimensional and preferable electrophoretic separation of components of the sample material is provided in areaof a separation plane. According to the invention it is proposed that the separation elementhas a channel or transfer structurefor the locally resolved discharge of separated sample components in a transport direction that is at right angles to the separation plane onto a support surfacethat is preferably suitable for mass spectroscopic analyses.

Separation method and device for protein mixtures

The present invention concerns a matrix reactor for reactions in which low-molecular and high-molecular reactants are involved wherein the reactor space Vcontains a matrix and comprises a reaction compartment and a supply compartment, wherein the matrix is composed of a porous material which can take up low-molecular reactants and wherein the exclusion volume Vof the matrix is available as the reaction compartment and the matrix volume Vof the matrix is available as the supply compartment. The matrix reactor can be used for enzymatic processes, in particular for a coupled in vitro transcription/translation reaction to produce proteins.

Matrix reactor and a method for producing products in said reactor

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Muensing, Germany

Albert Roeder