Alcon Laboratories, Inc.

Nestle S.a.

Alcon Manufacturing, Ltd.

Albert R Leboeuf

Mutlu Karakelle

Farhad H Namdaran

Stephen J Van Noy

Charles Freeman

Anilbhai S Patel

John W Sheets, Jr

Barbara A Piper

George Green

David Jinkerson

David L Jinkerson

High refractive index ophthalmic device materials

Bicomposite intraocular lenses having an anterior surface material different from a posterior surface material are disclosed. The posterior surface material reduces the risk of posterior capsule opacification.

Bicomposite intraocular lens and method for its preparation

Intraocular lens coating compositions for reducing the risk of posterior capsule opacification are disclosed. The coating materials, which differ from the substrate material, consist essentially of at least two aryl acrylic hydrophobic monomers of the formula

Intraocular lens coating compositions

Foldable, hydrophilic, ophthalmic device materials are cured by exposure to blue light using a benzoylphosphine oxide photoinitiator.

Method of preparing foldable hydrophilic ophthalmic device materials

High refractive index copolymers suitable for use in ophthalmic lenses, such as foldable intraocular lenses, are disclosed. The high refractive index copolymers of the present invention consist essentially of (i) one or more monomers having the structure: ##STR1## wherein: X is H or CH.sub.3 ; m is 0-10; Y is nothing, O, S, or NR wherein R is H, CH.sub.3, C.sub.n H.sub.2n+1 (n=1-10) iso OC.sub.3 H.sub.7, C.sub.6 H.sub.5, or CH.sub.2 C.sub.6 H.sub.5 ; Ar is any aromatic ring which can be unsubstituted or substituted with H, CH.sub.3, C.sub.2 H.sub.5, n--C.sub.3 H.sub.7, iso--C.sub.3 H.sub.7, OCH.sub.3, C.sub.6 H.sub.11, Cl, Br, C.sub.6 H.sub.5, or CH.sub.2 C.sub.6 H.sub.5 ; and (ii) one or more monomers having the structure: ##STR2## wherein: X, X' is independently H or CH.sub.3 ; n, n' are independently 2 or 3; m, m' are independently 2-25; Ar, Ar' are independently as defined above; a is 1 or 2; and Z is C(CH.sub.3).sub.2 or S(.dbd.O).sub.2.

Ophthalmic lens polymers

Foldable, acrylic, high refractive index ophthalmic device materials containing a UV absorbing chromophore are cured by exposure to blue light using a benzoylphosphine oxide photoinitiator.

Method of preparing foldable high refractive index acrylic ophthalmic

The tackiness associated with certain soft acrylic polymers can be reduced by plasma treatment of the polymer surface. This is particularly useful with regard to intraocular lenses (IOLs), especially foldable IOLs, which are made from such soft acrylic polymers.

Method for reducing taciness of soft acrylic polymers

Improved soft, foldable acrylic lens materials which are particularly suited for use as IOLs, but which are also useful as other ophthalmic devices, such as contact lenses, keratoprostheses, and corneal rings or inlays, are disclosed. These materials contain only two principal components: one aryl acrylic hydrophobic monomer and one hydrophilic monomer. The materials of the present invention are copolymers comprising at least about 90% by weight of the two principal monomeric components; provided that the amount of the hydrophilic component is not greater than that of the aryl acrylic hydrophobic component. The remainder of the material comprises up to 10% by weight of one or more additional components, such as cross-linking, UV-light absorbing, and blue-light absorbing components. The aryl acrylic hydrophobic monomers suitable for use in the materials of the present invention have the formula ##STR1## wherein: X is H or CH.sub.3 ;

High refractive index ophthalmic lens materials

Method for reducing tackiness of soft acrylic polymers

High refractive index copolymers comprised of monomers having the formula: ##STR1## wherein X is H or CH.sub.3 ;

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Fort Worth, TX, United States of America

Albert R Leboeuf