Janssen Pharmaceutica Nv

Albert Louis Willemsens

Marc Gaston Venet

Alex Herman Copmans

Alfons G De Knaep

Guido J Van Der Veken

Anna Maria Vandendriessche

Walter Louis Verstappen

Joannes Petrus Van Dun

Rudolf Albert

Eric J Guns

Jerome Albert Hoet

Wouter Louis Couck

A process for preparing (+)-6-�(4-chlorophenyl)(1H- 1,2,4-triazol-1-yl)methyl!-1-methyl-1H-benzotriazole comprising the resolution of (.+-.)-6-!(4-chlorophenyl)-hydrazinomethyl)-1-methyl-1H-benzotriazole and converting the appropriate enantiomerically pure hydrazine intermediate into (+)-6-�(4-chlorophenyl)(H- 1,2,4-triazol-1-yl)methyl!-1-methyl-1H-benzotriazole.

Process for preparing enantiomerically pure 6-{4-chlorophenyl) (1

Process for preparing enantiomerically pure 6-[(4-chlorophenyl)

A process for isolating levamisole or a therapeutically acceptable acid addition salt thereof from tetramisole or an acid addition salt thereof by precipitating levamisole. L-N-[(4-methoxyphenyl)sulfonyl]-glutamic acid (salt) and converting the diastereomeric salt into levamisole or a suitable acid addition salt thereof.

Process for isolating levamisole from tetramisole

An improved method of preparing 1-alkyl-3-carboxy-1H-pyrrole-2-acetic acids, the latter compounds being useful intermediates in the preparation of certain anti-inflammatory 1H-pyrrole-2-acetic acids.

Method of preparing 1-alkyl-3-carboxy-1H pyrrole-2-acetic acids

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Beerse, Belgium

Albert Louis Willemsens