Baxter International Inc.

Baxter Healthcare Inc.

Albert L Stone

John T Sorensen

Alexander S Borsanyi

Robert A Miller

Scott L Pool

Richard Harp

Robert Lebo

Roxanne Wall

Joseph Rondinone

Disclosed is a pneumatically-driven volume controlled bellows pump apparatus for oscillating liquid into a localized area of the human body, preferably methyl-tertiary butyl ether or another solvent, into the gallbladder. The pump includes a fluid reservoir in the form of an inverted syringe attached via a stopcock to the bellows. The bellows is attached via a second stopcock to a catheter also attached to a priming syringe. An inlet pinch valve is disposed between the bellows and the fluid reservoir and an outlet pinch valve between the bellows and the fluid receiver. To use the pump, a pigtail catheter with outlets in the pigtail is inserted into the desired area of the body, preferably a receptacle such as the gallbladder, to introduce a selected volume of liquid for gallstone dissolution. Liquid is infused into the receptacle by decompression of the bellows with the inlet but not the outlet valve open and then by compression of the bellows with the outlet but not the inlet valve open. Repeated infusion and aspiration is automatically accomplished by decompression and compression of the bellows with the inlet valve closed and the outlet valve open, or by compression and decompression of the bellows while the inlet valve is open and the outlet valve is closed alternated with compression and decompression while the inlet valve is closed and the outlet valve is open. Complete aspiration is accomplished by the use of a vacuum pump attached to the fluid reservoir. Also disclosed are syringe units and a transfer cap for use with the pump, together with a method for dissolving gallstones.

Multimodal displacement pump and dissolution system for same

A flexible collapsible container is filled with fluid by connecting a fluid conduit to a tubular port which communicates through one of the walls of the container to the container interior, and rupturing a sealing diaphragm that closes the bore of the tubular port. One then passes fluid through the conduit to fill the container. Thereafter, one seals either or both the tubular port and plastic wall which carries it to the other, opposed plastic wall of the container with seal line means to close off flow communication between the bore of the tubular port and a major portion of the container interior which contains the fluid. The effect of this is to block flow communication between the bore and the fluid so that the contents of the container remain sealed on disengagement of the fluid conduit from the tubular port.

Method for filling collapsible containers

Growing community of inventors

Laguna Hills, CA, United States of America

Albert L Stone