Amo Groningen B.v.

Stichting Voor De Technische Wetenschappen

Pharmacia Groningen Bv

Polyganics Bv

Orteq, B.v.

Albert Johan Pennings

Coenraad Jan Spaans

Ralf Guillaume Jean Catharina Heijkants

Jacqueline Hermina deGroot

Jacqueline De Groot

Leendert Willem Schwab

Arend Jan Schouten

Jacqueline Hermina De Groot

Ralph Vincent Van Calck

Frans Vincent Roukes

Folkert Gerhardus Dekens

Coenrad Jan Spaans

Ralf Guillaume Jean Catharine Heijkants

The invention presents a new method to prepare biomedical polyurethanes with high tensile and tear strengths. Such polyurethanes are especially interesting for making foams thereof, e.g. as meniscus implants. A new method, applicable to the biomedical polyurethanes, has been found to make such foams, that can be used as scaffolds. This method is based on salt leaching and phase separation.

Method for the preparation of new segmented polyurethanes with high tear and tensile strengths and method for making porous scaffolds

The present invention relates to a polyacylurethane having the following general formula (I) and a process for the preparation of such polyacylurethane. Preferred embodiments of the polyacylurethanes according to the invention have elastomeric properties. The polyacylurethanes can suitable be used in biodegradable, biocompatible and/or biomedical devices. 

Polyacylurethanes based on diisocyanates and polyesterpolyols

The present invention relates to new hydrogels with improved mechanical properties and methods of their preparation. The hydrogels are formed from hydrophilic polymers having function hydroxyl groups and have low elasticity modulus typically less than about 10 kPa, a tensile strength above 1 Mpa, an elongation above 50% which makes suitable as medical implants, in particular intraocular lenses. The hydrogels are prepared by a crosslinking method with a comparatively low concentration of hydrophilic polymer of a sufficiently high molecular weight dissolved in a good solvent.

Hydrogels and methods for their production

The present invention relates to new hydrogels with improved mechanical properties and methods of their preparation. The hydrogels are formed from hydrophilic polymers having function hydroxyl groups and have low elasticity modulus typically less than about 10 kPa, a tensile strength above 1 MPa, an elongation above 50% which makes suitable as medical implants, in particular intraocular lenses. The hydrogels are prepared by a crosslinking method with a comparatively low concentration of hydrophilic polymer of a sufficiently high molecular weight dissolved in a good solvent.

The invention is directed to a novel biomedical polyurethane based on diisocyanatae linked polyester polymer and diol components, said diol component having a uniform block-length.

Biomedical polyurethane, its preparation and use

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Maaseik, Belgium

Albert Johan Pennings