L'oreal

Societe L'oreal Sa

Nestec S.a.

Societe Des Produits Nestle S.a.

Albert Duranton

Francis Pruche

Jean-Thierry Simonnet

Lionel Breton

Didier Candau

Isabelle Hansenne

Olivier De Lacharriere

Michel Hocquaux

Yann Mahe

Quintino Gaetani

Hervé Richard

Christine Collin-Djangone

Andre Rougier

Brigitte Gautier

Nathalie Boyera

The invention relates to a method of treating and preventing ageing of the pilosebaceous unit and/or alopecia in human through the administration of taurine and/or hypotaurine and/or the acceptable salts thereof in an oral composition. Specifically, the invention relates to a method of treating and preventing miniaturization of the hair follicle. The invention also relates to the use of polyphenols to achieve these same ends. Finally, the invention relates to oral compositions that include polyphenols or taurine and/or hypotaurine and/or the acceptable salts thereof as active ingredients.

Use of taurine for treating alopecia

Expression of a messenger RNA which encodes a protein which is expressed by differentiated cells, notably the cells of the skin or appendages thereof, is inhibited by topically administering to said differentiated cells a thus effective amount of at least one double-stranded RNA oligonucleotide, formulated into a topically applicable, physiologically acceptable medium therefor; such regime or regimen is useful for treating a variety of afflictions or conditions, e.g., combating the signs of skin aging, stimulating hair growth or retarding loss thereof, inhibiting cellular proliferation and/or differentiation, etc.

Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA)

A kit includes at least one of: a substance for one of ingestion by a human body and application to one of the skin, the mucous membranes, hair, and the nails; a cosmetic applicator; and a makeup accessory. The kit also includes at least one of: an indicator of ambient humidity; and a sensor of ambient humidity.

Cosmetic kit including an indicator or sensor of ambient humidity

The present invention is directed to a method to promote, stimulate and/or delay hair loss by administering an effective amount of at least one bradykinin antagonists to promote, stimulate and/or delay hair loss to an individual in need thereof.

Method to promote, stimulate and/or delay hair loss by a brady kinin antagonist

The growth of body and/or head/cranial hair on mammalian organisms, for example humans, is modulated by administering thereto, whether topically and/or systemically, therapeutically effective amounts of at least one lipoxygenase or cyclooxygenase inhibitor, or at least one lipoxygenase or cyclooxygenase stimulator, preferably in the presence of at least one lipoxygenase/cyclooxygenase substrate or precursor thereof; when a hair-growth or hair loss-limiting response is sought to be elicited, a lipoxygenase inhibitor and/or cyclooxygenase stimulator is administered (conversely, to reduce or prevent hair growth, a lipoxygenase stimulator and/or cyclooxygenase inhibitor is administered).

Modulating body/cranial hair growth

Use as additives, in cosmetic compositions, of a peptide containing the sequence Lysine-Proline-Valine, with the aim of preventing or reducing the intolerance reactions linked to a contact hypersensitivity.

Use of a peptide preventing the intolerance reactions of the skin, in particular in cosmetic compositions

Use of alkyl polyglycosides and/or of O-acylated derivatives of glucose for treating hair loss

The loss of body/cranial hair is promoted and/or its growth is slowed/prevented by topically and/or systemically administering to an individual in need of such treatment respectively effective amounts at least one lipoxygenase inhibitor and at least one cyclooxygenase inhibitor, or alternatively, an effective amount of an active agent that is both a lipoxygenase inhibitor and a cyclooxygenase inhibitor.

Modulating body/cranial hair growth with lipoxygenase/cyclooxygenase

Multicomponent agent or kit for preparing the sulpho-conjugated form of pyridino, pyrimidino or triazino N-oxide compounds and method of use. The present invention relates to a multicomponent agent or kit for preparing the sulpho-conjugated form of pyridino, pyrimidino or triazino N-oxide compounds,

Growing community of inventors

Maisons-Laffitte, France

Albert Duranton