Merial Limited

Boehringer Ingelheim Animal Health USA Inc.

Albert Boeckh

Ernst Baumann

Mark Soll

Luiz Gustavo Cramer

Matthias Pohlman

Philippe Jeannin

Mark D Soll

Mark David Soll

Natalya Shub

Monica Tejwani-Motwani

Robert P Waranis

Jeffrey Norman Clark

Kerrie Maria Powell

Peter Johannes Van Eijk

Ronus De Bode

Peter Johannes Sevaas Savio Van Eijk

The present invention provides for, inter alia, novel topical formulations comprising at least one 1-N-arypyrazole derivative and amitraz and to methods for treating, controlling, or preventing parasite infestations on mammals or birds The inventive formulations include spot-on, pour-on or spray formulations and may include a further ectoparasiticide, such as an IGR compound, an avermectin or milbemycin derivative, or a pyrethroid insecticides, and anthelmintics, such as benzimidazoles and imidazothiazoles. The inventive formulation provides a larger duration of parasite control at a faster rate of control. The inventive formula remains effective up to three months from the first application. Moreover, the inventive formulations prevent tick attachment to the animal, thereby providing protection against tick borne diseases. The ectoparasites which may be controlled, treated or prevented by the present invention includes ticks, fleas, mites, mange, lice, mosquitoes, flies and cattle grubs.

Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz

Provided is a novel ivermectin derivative and compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: 

Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds

This invention provides for a method for preventing or interrupting the transmission of anthropod and mosquito-borne diseases from a first actual or putative amplifying or incipient host to a second actual or putative amplifying or incipient host, which comprises applying or administering a formulation comprising an effective amount of at least one 1-N-arylpyrazole to said first actual or putative amplifying host and/or actual or putative amplifying or incipient host. This invention also provides for a method of using a bait placed in a bird station, the bait comprises an affective amount of at least one 1-N-arylpyrazole either alone or in combination with an antiparasitic, antihelmintic, or insecticidal agents. This invention also provides for an apparatus for delivering an effective amount of a formulation according to the present invention to a bird or animal in an environment where it resides.

1-N-arylpyrazole derivatives in prevention of arthropod-borne and mosquito-borne diseases

In particular this invention provides for spot-on compositions for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: The invention also provides for a method of treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal treating parasitic infestations or for the prophylaxis of parasite infestations in mammals or birds which comprises topically applying to said mammal or bird an effective amount of a composition according to the present invention.

Spot-on formulations for combating parasites

Growing community of inventors

Cumming, GA, United States of America

Albert Boeckh