Ge Healthcare UK Limited

Global Life Sciences Solutions Operations UK Ltd

Alan Stuart Pierce

Cheryl Louise Potts

Simon Laurence John Stubbs

David Gwyn Treharne

Peter James Tatnell

Jeffrey Kenneth Horton

Geraint Seymour

Neil John Williams

Samantha Jane Ogden

Michael John Smith

Stevan Paul Tortorella

Kathryn Louise Lamerton

Christopher Burrows

Alison Myfanwy Wakefield

Rebecca Ngaire Fullerton

Alexander Schenk

Christopher George Norey

Robert John

Matthew Sam Morrison

Jared William Harris Evans

Ashley Edward Bryant

Sean Robert Sweeney

David Powell

Elizabeth Ashman

Disclosed is a microfluidic device including a reagent supply apparatus comprising: a solid supportformed preferably from cellulose fibrous material having a porosity which allows liquid flow through the material; at least one generally dry reagentstored on a surface of the support at a regent location or locations; the support further being suitable for storing biological sample materialin a dry state at a sample location or locations, spaced from the reagent location or locations.

Microfluidic devices and arrangements for supplying such devices with reagents and biological samples

The present invention relates to a device and method for sample preparation and collection. More closely the invention relates to a device to isolate DNA, RNA and proteins or other biomolecules in one single step from the same undivided sample.

Device and method for sample isolation

Disclosed is a method for detecting and quantifying gut flora derived from human faeces, comprising acquiring a solid support containing human faeces; optionally amplifying nucleic acid from the human faeces; and detecting and quantifying the presence of gut flora of interest. Also disclosed is a method for assessing whether a person has type-2 diabetes as well as a kit for detecting and quantifying gut flora from human faeces, comprising a solid support for collecting human faeces; and primer pairs for amplifying 16S rRNA sequence from bacteria of interest.

Screening and monitoring the progression of type 2 diabetes by the molecular identification of human gut flora using FTA as a faecal collection device

Disclosed is a biological sample collectorcomprising a solid supporthaving plural discrete areas (FIG.) for accepting a biological sample, each area being chemically differentiated, for example by having a different chemical treatment sorbed onto the solid support. An envelopeencloses the solid support. A cover portioncan cover the biological sample after collection to prevent infection. UV light can be applied to the collected sample to reduce the risk of infection.

Biological sample collectors and handling thereof

Methods of using a biological sample collection device comprising a collection portion and a body portion, the body portion including a holding portion for holding a biological sample storage medium, and a sample transfer means, such as a cover. The collection portion can be arranged in a first position separated from the body portion for collecting a sample, and in a second position at least partly between the sample transfer means and the holding portion, with the sample transfer means being operable to push the collection portion towards a position at which the holding means is arranged to hold the biological sample storage medium, enabling a sample held in the collection portion to be transferred to the latter.

Biological sample collection device

A controlled transfer biological sample material collection device is disclosed which includes a body and a sample collection member for collecting the biological sample material, the body housing a sample storage medium for generally dry storage of the biological material, the collection member being moveable from an exposed position where collection of a biological sample is possible, to a transfer position which effects transfer of at least a portion of the collected sample to said medium. The body of the device slideably supports the sample collection member, and the body or collection member includes a ramp-like projection portion operable to force the collection member into the transfer position against the medium and to effect the transfer as the collection member slides within the body.

Controlled transfer biological sample collection devices and methods of using such devices

A controlled transfer biological sample material collection device is disclosed which comprises: a body; and a sample collection member for collecting the biological sample material (not shown), the body housing a sample storage medium for generally dry storage of the biological material, the collection member being moveable from an exposed position (shown in FIG.) where collection of a biological sample is possible, to a transfer position (shown in FIG.) which effects transfer of at least a portion of the collected sample to said medium. The device is characterized in that the body slideably supports the sample collection member, and in that the body or collection member include a ramp-like projection portion (FIG.) operable to force the collection member into the transfer position against the medium and to effect said transfer as the collection member slides within the body.

Biological samples, such as saliva, are commonly collected on a swab and subsequently transferred to an absorbent storage medium. Embodiments of the present invention provide a biological sample collection devicecomprising a collection portionand a body portion, the body portion including a holding portionfor holding a biological sample storage medium (FIG.), and a sample collection/transfer means. The collection portioncan be arranged in a first position shown in FIG., separated from the body portion for collecting a sample. The device employs depressible latches (FIG.) to control the movements of the collection portion.

Biological samples, such as saliva, are commonly collected on a swab and subsequently transferred to an absorbent storage medium. Embodiments of the present invention provide a biological sample collection device comprising a collection portion and a body portion, the body portion including a holding portion for holding a biological sample storage medium, and a sample transfer means, such as a cover. The collection portion can be arranged in a first position separated from the body portion for collecting a sample, and in a second position at least partly between the sample transfer means and the holding portion, with the sample transfer means being operable to push the collection portion towards a position at which the holding means is arranged to hold the biological sample storage medium, enabling a sample held in the collection portion to be transferred to the latter. This provides an improved means of collecting a biological sample.

Growing community of inventors

Cardiff, United Kingdom

Alan Stuart Pierce