Gw Research Limited

Jazz Pharmaceuticals Research UK Limited

Kind Consumer Limited

Alan Silcock

Benjamin Whalley

Royston Gray

Jitinder Wilkhu

Alexander Cobb

Hannah Straker

Karen Tse

Laura Bryant

The present invention relates to a group of cannabinoid derivatives as pharmaceutically active compounds and methods of preparation thereof. The cannabinoid derivatives of the invention are analogues of cannabidiol (CBD). CBD is a non-psychoactive cannabinoid which has been used to treat various diseases and disorders. While such treatments hold promise, there remains a need in the art for more effective treatments and this has been brought about by way of the cannabinoid derivatives of the invention

Cannabinoid derivatives as pharmaceutically active compounds and methods of preparation thereof

The present disclosure provides a microparticulate comprising one or more cannabinoids and a pH dependent release polymer. In embodiments, the one or more cannabinoids are present in an amount ranging from 10% w/w to about 50% w/w. In embodiments, the pH dependent release polymer is present in an amount ranging from ranging from about 5% w/w to about 85% w/w.

pH dependent release coated microparticle cannabinoid formulations

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Cambridge, United Kingdom

Alan Silcock