Other

Hoffmann-la Roche Inc.

Ambit Biosciences Corporation

Oxigene, Inc.

Globalytica, LLC

Alan N Schwartz

Thomas D Theisen

Stephan D Parent

Shripad S Bhagwat

Valeriya N Smolenskaya

Wei Lai

Magdalena Usategui

Alan J McNally

Karl L Ginter

David L Coffen

Ronald W Pero

Melanie Janelle Bevill

David J Chaplin

Pradeep B Madan

Melanie J Roe

Randolph Pherson

Sarah Beebe

Mike Bartman

Katherine Pherson

Ronald J Sweren

Diana Manfredi

Anders Olsson

Grace Scarborough

Tomas Ekberg

A local positioning system (LPS) is provided. The LPS includes at least three local position tracking devices, each further including one or more of: a clock synchronized to the clock in each of the other devices; a transmitter transmitting signals over time synchronized to the clock; and a receiver receiving the signals over time from the other devices. The LPS further includes a processor operatively coupled to at least one of the devices and that is configured to: obtain for each of the signals a location of the device that transmitted that signal; produce one or more representations of at least a part of a living body based on at least one of one or more of the locations and one or more further representations of the at least the part of the living body, each of the representations including one or more temporal frames; and to provide output.

Localization of the parathyroid

A female insertion system is provided. The system includes a conformable insert shaped for insertion into one or more structures of a female human that are associated with at least one of reproduction and one or more erogenous zones; one or more sensors, at least one of the sensors included in the insert, and configured to measure and to relay data, wherein the data is acquired on one of a one-time basis and a multiple-time basis included one of a non-continuous period, a continuous period, and an intermittent temporal period; and a processor configured to: control the insert; generate a treatment for one of the structures of the female human; store the data; and based on the data, automatically affect one or more of the structures via the insert.

Female insertion system

In one embodiment, a wearable assembly that includes a plurality of components is provided. The components include an eyepiece assembly fittable over a portion of a wearer's face, the eyepiece assembly including one or more strands, at least a portion of the eyepiece assembly including a phase change material, wherein a shape of the eyepiece assembly changes upon an application of an energy to the phase changing portion to one or more of conform and contour to one or more features of the wearer's face; and nosepiece connected to the eyepiece assembly.

Wearable assembly

A vaginal device is described. A conformable vaginal insert is shaped for insertion into a vaginal cavity of a female human. A contact point is configured to change a shape of the insert. A sensor is configured to measure and to relay characteristics of the vaginal cavity and the surrounding and supportive structures of the vaginal cavity. A processor is configured to control the contact point to adjust the shape of the insert, generate a treatment for the vaginal cavity and the surrounding structures of the vaginal cavity and the supportive structures of the vaginal cavity comprising a vaginal cavity profile generated from the measured characteristics, store the measured characteristics and the vaginal cavity profile, and based on the stored measured characteristics and the stored vaginal cavity profile, automatically modify the shape of the insert by control of the contact point to provide the treatment to the vaginal cavity.

Apparatus for effecting feedback of vaginal cavity physiology

Systems and methods are disclosed for locating the parathyroid. In one aspect, temporal variation among a plurality of images is evaluated and at least one image is enhanced according to the temporal variation. The image may be enhanced to one or both of reduce conspicuity of the thyroid gland and enhance conspicuity of the parathyroid gland. Some of the plurality of images may be adjusted in order to align representations of a target portions. Adjustments may be based locations of one or more organs or one or more artificial markers affixed to a living body in the plurality of images. A local positioning system (LPS), GPS, or other locating system may be used to position a living body, align the plurality of images, or to guide the positioning of objects relative to the living body. An elastomeric gel marker for imaging applications is also disclosed.

A system is described. A computing processor is configured to: represent recorded data capable of being consciously experienced by a user through a sensory form as an indexed sequence and maintain the indexed sequence; provide the recorded data to the user in the sensory form while the user is being monitored for a plurality of points in the indexed sequence at which electrical neural signals as evoked by the user in reaction to the providing of the recorded data, are captured; pair the signals with portions of the recorded data corresponding to the plurality of points at which the signals were evoked and reorganize the recorded data as categorized by the signals; measure and analyze the signals to identify one or more physiologic responses that fall below the levels of self-awareness and cognitive awareness; and inform the user of the one or more physiologic responses.

System for individualized data education

A pair of eye goggles is provided. The pair of eye goggles includes a nosepiece fittable over a portion of a wearer's face, the nosepiece comprising one or more strands, at least a portion of the nosepiece comprising a phase change material, wherein a shape of the nosepiece changes upon an application of an energy to the phase changing portion to conform to the face; and a pair of eyepieces connected to the nosepiece.

Pair of eye goggles

A penile condom catheter facilitates urine collection and egress of urinary fluids away from the body torso. A circumferential anchoring structure includes a web of flexible strands sized and arranged to at least partially contact a portion of the penis. The anchoring structure provides a flexible yet secure hold against the penis when flaccid and provides an increase in the hold when a longitudinal force is exerted upon the anchoring structure. An annularly circumferential penile skin covering material is affixed to the anchoring structure and sized to fit over at least a portion of the penis. A seal is affixed to at least a portion of a covering material, a covering material orifice, or an anchoring structure. A conduit is affixed to at least one of a covering material, a covering material orifice, a seal and an anchoring structure created to permit the flow of urinary fluid away.

Penile condom catheter for facilitating urine collection and egress of urinary fluids away from the body torso

A method is described. Recorded data capable of being consciously experienced by a user through a sensory form is represented as an indexed digital sequence and maintaining the indexed digital sequence in a storage device. The data is provided to the user via an output device capable of reproducing the data in the sensory form while the user is monitored with a monitor device for a point at which a non-conscious stimuli, as evoked by the user in reaction to the providing of the data, is captured. The stimuli as captured by the monitor device is paired using a processing device with a portion of the data corresponding to the point at which the stimuli was evoked and the data in the storage is reorganized with the processing device as categorized by the stimuli. The output device is configured to efficiently provide the reorganized data as personalized to the user.

System and method for individualized data education system

An instrument for therapeutically cytotoxically ablating parathyroidal tissue is disclosed. A substance is capable of transforming the parathyroid gland from overproduction of parathyroid hormone when the substance's quantity exceeds a set amount, and is capable of transforming the parathyroid gland from overproduction only when activated by application of sufficient units of an electromagnetic energy having a frequency ranging from 400 THz to 30 PHz when the substance's quantity is below the set amount. A delivery device is operable to introduce the substance into the parathyroidal tissue and to quantitatively limit the quantity to below the set amount. An energy device is operable to apply units of the electromagnetic energy after the substance has been introduced. A sensor is operable to monitor the activation of the substance as the electromagnetic energy is applied. The energy device is further operable to modulate applying the electromagnetic energy when the substance has been activated.

Instrument for therapeutically cytotoxically ablating parathyroidal tissue within a parathyroid gland

An ostomy pouching system is described. A baseplate includes a seal adapted to be securely placed on the skin about the perimeter of tissue defining a stoma incised into a patient. An ostomy reservoir forms a sealed space within which discharge can be received and held. A flex layer includes a seal that is airtight, watertight, or both, and which is structurally interposed between at least a portion of two or more of the skin, tissue, stoma, baseplate, and ostomy reservoir. The flex layer includes a resiliently and elastically malleable phase change material. The flex layer is deformable such that at least one portion of the flex layer can transmute the magnitude of a force applied to the flex layer and redirect the force. External forces acting upon at least one of the skin, tissue, stoma, baseplate, and ostomy reservoir are mitigated, transmuted, and isolated by the flex layer.

Ostomy pouching system

The subject matter described herein is designed to facilitate and overcome the limitations of rehabilitation of body changes and to improve, retrain, and facilitate body functions micturition, defecation, sexual pleasure, anatomic prolapse, and their related bodily dysfunctions. The devices can include sensor, optics, send and receive transmitters, local positioning system (LPS) or sensors, computing devices and display elements and devices, which can be powered by bio-generating machines and devices.

A pair of eye goggles is described. The eye googles include a three axial adjustable nosepiece that can be fit over a wearer's nose including a plurality of unequal length strands on each side of the nosepiece with the strands comprising resilient properties different from the resilient properties included in the other strands in the plurality of strands on that side. The eye goggles also include a strap that can be fit removably around the wearer's head, and a pair of eyepieces. Each eyepiece includes a transparent lens that can be fit over one of the wearer's eyes, and a frame that surrounds the transparent lens to which the nosepiece and the strap are attached. The eye goggles also include a sealing pad formed on an inside-facing edge of the frame.

Growing community of inventors

Edmonds, WA, United States of America

Alan N Schwartz