University of Michigan

Alan Hunt

Edgar Meyhofer

Greg Spooner

John A Nees

Ajit P Joglekar

Lingjie Jay Guo

Raoul Kopelman

Brandon H McNaughton

Roy Clarke

Gerard A Mourou

Paivo Kinnunen

Remy Elbez

Irene Sinn

Theodore Albertson

Gerald Mourou

Jeremy Damon Hoff

Li-Jing Cheng

Described herein are various methods, devices and systems for performing asynchronous magnetic bead rotation (AMBR) to detect and monitor cellular growth and/or behavior. Cluster rotation of magnetic particles for AMBR is descried. In particular, described herein are systems for the parallel analysis of multiple wells of a sample plate. Also described herein are methods for controlling the illumination and imaging of rotating magnetic particles.

Asynchronous magnetic bead rotation sensing systems and methods

Here is presented a versatile technique for machining of nanometer-scale features using tightly-focused ultrashort laser pulses. By the invention, the size of features can be reduced far below the wavelength of light, thus enabling nanomachining of a wide range of materials. The features may be extremely small (&#x3c;20 nm) and are highly reproducible.

Method for forming nanoscale features

A support for immobilizing target molecules comprises a substrate having a plurality of binding regions for binding select target molecules, with target-molecule-capturing agent immobilized at the binding regions. The binding regions are intersperse among other non-binding regions. The binding regions are of sub-micron size, have high selectivity and high binding capacity, and prevent or at least minimize loss of target molecule activity.

Nanoscale patterning and immobilization of bio-molecules

Growing community of inventors

Plymouth, MI, United States of America

Alan Hunt