Other

Janssen Biotech, Inc.

Alan H Gibbs

Yi Liu

Michael J Hunter

Alan Wickenden

Mack Flinspach

Robert Neff

William Eckert

The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, methods of making and using the foregoing, and methods of alleviating pain with peptide inhibitors of Nav1.7.

Huwentoxin-IV variants and methods of use

The present invention relates to Huwentoxin-IV variants, polynucleotides encoding them, and methods of making and using the foregoing.

A pressure wave motor that may be a fluid driven device with a continuous reciprocating driven member, the sole moving part, for connection into an appropriate non compressable fluid supply system that sustains pressure waves and that allows the reciprocating driven member to generate a usable harmonic pressure wave for use in sustaining continuous reciprocation of the driven member along with fluid flow. The pressure wave motor is driven solely by the fluid supply input fluid which is a liquid and the forces the input fluid generated by continuous reciprocation of the driven member for producing work without additional moving parts. The fluid supply system may be a normal household water supply system. The fluid driven device can produce a pulsating fluid output that may be used for cleaning and massaging. The fluid driven device includes a driven member cavity, the inlet connected to the cavity, a main outlet connected to the member cavity, a second outlet connected to the member cavity, and a control system. The pressure wave motor may be self-starting and the second outlet includes a variable fluid volume chamber between the member cavity and the second outlet. A variable valve may be used at the outlets to vary the rate of reciprocation of the driven member.

Fluid device

Fluid driven device connected into a fluid supply system

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Miami, FL, United States of America

Alan H Gibbs