Lectec Corporation

Other

Alan C Hymes

Lincoln T Ong

Garry R Persons

Jane Nichols

The skin disorder acne, as well as one or more isolated pimples, are treated by applying to the skin, over the skin disorder, a flexible moisture-containing hydrophilic hydrogel patch that includes a backing support such as paper, cloth or plastic and a water-based hydrogel layer applied to the backing. The hydrogel layer comprises a hydrophilic natural or synthetic polymer dispersed in water to provide body and can be a tacky adhesive. The polymer can comprise any high molecular weight hydrophilic carbohydrate such as karaya, cornstarch, or kelp and/or a synthetic hydrophilic polymer such as polyacrylamide or polyacrylic acid. A humectant such as an alcohol containing two or more hydroxyl groups, i.e., a polyhydric alcohol, keeps the adhesive layer moist. A solute such as salt, protein, sugar or an alcohol is dissolved in the water in a quantity sufficient to raise the osmotic pressure enough to maintain the adhesive hydrogel layer in a hypertonic state with respect to the underlying skin tissue. The hydrogel adhesive which hydrates the upper layer of skin forms a hydrophilic bridge with the patient's skin that allows fluid to be drawn by osmotic pressure from the skin disorder through the normally dry stratum corneum into the patch. Another aspect of the invention is the a hypertonic moisture-containing adhesive patch itself.

Therapeutic method for treating acne or isolated pimples and adhesive patch therefor

Blisters of the skin are treated by applying to the skin over the blister a flexible moisture-containing hydrophilic hydrogel patch that includes a backing support such as paper, cloth or plastic and a water-based hydrogel layer applied to the backing. The hydrogel layer comprises a hydrophilic natural or synthetic polymer to provide body dispersed in water and can be a tacky adhesive. The polymer can comprise any high molecular weight hydrophilic carbohydrate such as karaya, cornstarch, or a kelp gel and/or a synthetic hydrophilic polymer such as polyacrylamide or polyacrylic acid. A humectant such as a polyhydric alcohol, keeps the gel layer moist. A solute such as salt, protein, sugar or an alcohol is dissolved in the water in a quantity sufficient to raise the osmotic pressure enough to maintain the hydrogel layer in a hypertonic state with respect to the blister. The hydrogel which hydrates the normally dry upper layer of skin forms a hydrophilic bridge with the patient's skin that allows fluid to be drawn by osmotic pressure from the blister through the normally dry stratum corneum into the patch. In addition, the hydrogel very quickly significantly dimishes the pain secondary to skin burns and blisters.

Treating traumatic burns or blisters of the skin

A flexible, liquid-absorbing, adhesive skin reservoir includes a backing element and a substrate attached to the backing element. The substrate comprises a homogeneous, hydrophilic, stable matrix including a solid phase formed of a synthetic polymer and/or a long chain natural or synthetic polysaccharide, or a combination thereof. The liquid phase of the matrix consists of water, hydric alcohol, carbohydrates and/or proteins in an aqueous solution, and/or a combination thereof. The matrix contains a medicament therein for release to the affected areas for local and/or systemic medicinal effect.

Drug dispensing device for transdermal delivery of medicaments

A flexible, liquid absorbent, adhesive bandage includes a backing element and a substrate attached to the backing element. The substrate comprises a homogeneous, hydrophilic, stable matrix including a solid phase formed of a synthetic polymer, a long chain polysaccharide, or a combination thereof. The liquid phase of the matrix consists of a hydric alcohol, carbohydrates and/or proteins in an aqueous solution, and/or water or a combination thereof. The matrix contains a medicament therein for release to the affected areas.

Sterile improved bandage containing a medicament

A flexible, liquid absorbent, adhesive bandage includes a backing element and a substrate attached to the backing element. The substrate comprises a homogeneous, hydrophilic, stable matrix including a solid phase formed of a synthetic polymer, a long chain polysaccharide, or a combination thereof. The liquid phase of the matrix consists of a hydric alcohol, carbohydrates or proteins.

Sterile improved bandage and sealant

An improved combination electrode for use in monitoring and stimulation medical applications is provided having an electrical current conductor including a connector plug and a skin-interfacing substrate material, this substrate being a composition including a karaya gum matrix containing an electrically conductive substance.

Monitoring and stimulation electrode

An improved combination electrode for use in monitoring and stimulation medical applications is provided having an electrical current conductor including a connector plug and a skin-interfacing substrate material, this substrate being a composition such as mixture of a natural organic polysaccharide and hydric alcohol having electrically conductive and adhesive properties.

Growing community of inventors

Hopkins, MN, United States of America

Alan C Hymes