Cook Incorporated

Alan A Eller

Thomas A Osborne

Ram H Paul, Jr

Christopher G Dixon

Aaron Barr

Christopher L Hruska

An intraluminal device is provided with a structural member having an abluminal surface to engage a vessel wall and a luminal surface. The structural member is formed with regions having different thicknesses between the abluminal surface and luminal surface. The intraluminal device may be useful where improved axial flexibility is desired.

Intraluminal device with flexible regions

An iris-type valve assembly comprises a base, a rotatable member, and an elongated elastomeric valve sheath. The distal end of the valve sheath is secured to the base, and the proximal end of the valve sheath is secured to the rotatable member. At least one of the valve sheath ends includes a flange that is secured to a valve-receiving surface of the base or the rotatable member. The base and the rotatable member are aligned to define a passageway therethrough for passage of an interventional device. The valve sheath is disposed along the passageway and has a longitudinal opening therethrough for passage of the interventional device. Upon rotation of the rotatable member relative to the base, the longitudinal opening of the valve sheath is selectively constrictable to comprise a seal around the interventional device.

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Plainfield, IN, United States of America

Alan A Eller