Delalande S.a.

Alain Y Platel

Guy R Bourgery

Alain P Lacour

Patrick G Guerret

Alain Lacour, Deceased

Compounds of formula: ##STR1## wherein: Ar is an aromatic group; R and R.sub.1 are H or CH.sub.3 ; A represents a nitrogenized heterocyclic radical; B is OH or forms with the adjacent CO group, either an amido group, or a carbonyloxy group; R.sub.2 and R.sub.3 are H or alkyl; m=0 or 1; and n=0, 1, 2 or 3. These compounds are useful as drugs having stimulating, protecting and/or correcting activities of the cerebral functions.

New cinnamoic compounds, the process for preparing same and the use

New derivatives are provided corresponding to the formula: ##STR1## in which Ar represents an aromatic nucleus; and X represents: either the trans ##STR2## chain or the ##STR3## chain and A=CONHOH, COOEt, COOH or CONR.sub.2 R.sub.3, either the trans-CH.dbd.CH--CH.sub.2 -- chain or --CH.sub.2 --CH.sub.2 --CH.sub.2 chain and A=carboxamido, N-isopropylcarboxamido, pyrrolidinocarbonyl or piperidinocarbonyl. These derivatives and their salts are used as drug for their activity stimulating, protecting and/or correcting cerebral functions.

Arylic derivatives of piperazine, the method of preparing same and their

A class of known (1-cinnamoyl or 1-phenylethylcarbonyl) piperazine derivatives have been found to be central nervous system stimulants effective to improve the mental alertness and to brighten the spirits of human beings.

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Rueil Malmaison, France

Alain Y Platel