Biomerieux, Inc.

Other

Alain Theretz

Bruno Colin

Bernard F Mandrand

Yves Fouillet

Agn&egrave;s Perrin

Fran&ccedil;ois Mallet

Michel Goudard

Eric Perouzel

Agnès Perrin

Agn&eacute;s Perrin

Christine Hebrard

The present invention relates to a method for simultaneously detecting hybridization reactions and immunoreactions in a sample which may contain target analytes consisting of at least one nucleic acid and of at least one other ligand that is different in nature, characterized in that it comprises the steps consisting in: The invention also relates to the use of this method in diagnosis and the biological or diagnostic test kits that are useful for carrying out the method of the invention.

Method for simultaneously detecting hybridization reactions and immuno-reactions, and its uses in diagnosis

The invention concerns a method for fixing a biological molecule, associated with a specific binding site, on the surface of a support made of silica or metal oxide. The invention also concerns a surface functionalized by the method and the use of such a surface. The method is characterized in that it consists in: functionalizing the surface by cleaning, using at least a solvent or an oxygen plasma or any other process for forming alcohol groups on the support surface, to make it hydrophilic; contacting the biological molecule on said functionalized surface; and functionalizing the support by fixing the biological molecule specific binding site on at least one of the support alcohol groups. The invention is particularly useful in the field of biomedical diagnosis.

Attaching a biological molecule to a support surface

Method for determining an analyte present in a solution

The present invention relates to a method for at least one of detecting, quantifying or isolating at least one analyte from a liquid medium in which the analyte is distributed and comprises providing a reagent comprised of particles having a receptor for an analyte fixed to the particles distributed in the medium and a capturing means having an exposed surface defining an active zone. An intermediate reagent is formed by the complex of the reagent with the analyte. A second receptor is fixed in the active zone to capture either the analyte bound by the reagent or the receptor (capture partners). The active zone serves as a site of isolation and concentration of the capture partners.

Method for isolating, in particular for detecting or quantifying an analyte in a medium

Method and device for the determination of an analyte using super

Method and device for determining an analyte in a sample

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Ecully, France

Alain Theretz