Meiji Seika Kaisha, Ltd.

Meiji Seika Pharma Co., Ltd.

Meiji Seika Kabushiki Kaisha

Akitaka Nakane

Koji Yanai

Jinichiro Koga

Toshiaki Kono

Yuko Baba

Hidetoshi Kubota

Naomi Sumida

Tomoko Nishimura

Takeshi Murakami

Shuichi Gomi

Tatsuki Moriya

Koichiro Murashima

Takayoshi Fukushima

Hirofumi Nakamura

Takashi Yaguchi

Kaoru Okakura

Fumikazu Yokoyama

Masao Hirayama

Atsushi Inoue

Masato Tani

Kouichirou Murashima

Goh Tsujiuchi

Satoshi Hanamura

Yuko Nakamura

Toshiaki Nagasato

Yasumasa Ota

Akemi Watabe

Naomi Pharmaceutical Technology Labs Sumida

Takeshi Pharmaceutical Technology Labs Murakami

Koji Pharmaceutical Technology Labs Yanai

Yuko Bioscience Labs Meiji Seika Kaisha Ltd Baba

Tatsuki Pharmaceutical Technology Labs Moriya

Yuko Bioscience Labs Meiji Seika Kaisha Ltd Nakamura

Takashi Pharmaceutical Research Center Yaguchi

A modified polynucleotide has a different base sequence in at least one codon from a wild-type base sequence encoding a horseradish peroxidase polypeptide. The usage frequency of the modified codon of the polynucleotide corresponds to the codon usage frequencies of three filamentous fungal species in, and. The polynucleotide is capable of expressing the polypeptide to be encoded in a filamentous fungus.

Method for producing horseradish peroxidase recombinant protein using filamentous fungus

The present invention relates to novel aminoglycoside antibiotics, a process for producing the same, and pharmaceutical use thereof. More specifically, the present invention relates to compounds represented by formula (I), a process for producing the same, and use of the same as antimicrobial agents. wherein R represents amino or hydroxyl.

Aminoglycoside antibiotics, process for producing the same, and pharmaceutical use thereof

A novel endoglucanase PPCE derived from, a cellulase preparation containing the endoglucanase PPCE, and a method of treating a cellulose-containing fabric utilizing the endoglucanase PPCE or the cellulase preparation, are disclosed. The endoglucanase PPCE is highly active to a fabric, and has a low optimum temperature and a strongly acidic optimum pH.

Endoglucanase PPCE and cellulase preparation containing the same

An object of the present invention is to provide a &#x3b2;-fructofuranosidase variant whose reaction specificity is improved to be suitable for the production of fructooligosaccharides. According to the present invention, there is provided a &#x3b2;-fructofuranosidase variant consisting of a mutated amino acid sequence of SEQ ID NO: 2 or a mutated homologue thereof, which has mutations at specific amino acid residues.

&#x3b2;-fructofuranosidase variants

A novel endoglucanase derived from, a polynucleotide encoding the endoglucanase, and a cellulase preparation containing the endoglucanase are disclosed. The endoglucanase or cellulase preparation is available for a washing use or fabric processing, such as a color clarification of a cellulose-containing fabric, a reduction of fuzz, an improvement of the touch feel and appearance of the fabric, providing a localized color change to the fabric, or a reduction of stiffness.

Endoglucanase STCE and cellulase preparation containing the same

This invention relates to a protein that is a-derived endoglucanase lacking the cellulose-binding domain and exhibits endoglucanase activity, and a method for using the same. This invention can enhance effects of an endoglucanase enzyme on fabric treatment such as reduction of fuzzing, improvement in feel and appearance, color clarification, partial color change, and softening of cellulose-containing fabrics and on performance improvement in the deinking of waste paper and drainage of paper pulp.

[object Object]

A cellulase preparation comprising an endoglucanase derived from Zygomycetes, a cellulose-binding-domain-deleted endoglucanase, or a modified or homologous protein thereof, together with a reducing agent is disclosed. Further, a method of treating cellulose-containing fabric, comprising the step of treating the fabric with the cellulase preparation to improve a property of the fabric, a method of deinking waste paper, comprising the step of treating the waste paper with the cellulase preparation. together with a deinking agent, and a method of improving freeness of paper pulp, comprising the step of treating the paper pulp with the cellulase preparation, are disclosed.

Cellulase preparations containing reducing agent and method of processing fiber

There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.

Endoglucanase enzyme NCE5 and cellulase preparations containing the same

The present invention relates to a cellulase preparation comprising nonionic surfactants together with endoglucanases derived from Zygomycetes; a detergent composition comprising the above cellulase preparation with detergent components; a method of treating fabric which comprises treating cellulose-containing fabric with the above cellulase preparation so as to improve the properties of the fabric; a method of deinking waster paper which comprises a step of treating waste paper with the above cellulase preparation together with a deinking agent; and a method of improving the freeness of paper pulp which comprises a step of treating paper pulp with the above cellulase preparation.

Cellulase preparation containing nonionic surfactant and method of treating fiber

It is an object of the present invention to provide enzymes that have high endoglucanase activity and yet exhibit high activity even under alkaline conditions, and genes encoding the same. The enzyme according to the invention has the following properties: a) exhibiting endoglucanase activity; and b) capable of completely removing fuzz from regenerated cellulose fabrics at a concentration of 1 mg of the protein/L or below. The enzyme of the invention having endoglucanase activity is a protein comprising the amino acid sequence as shown in SEQ ID NO: 1, 3, 5, 7, 9 or 11; a modified protein thereof exhibiting endoglucanase activity; or a homologue of the protein or the modified protein.

Endoglucanases and cellulase preparations containing the same

A novel &bgr;-fructofuranosidase and its gene are disclosed. A polypeptide comprising the amino acid sequence of SEQ ID No. 1 or No. 3 is an enzyme having &bgr;-fructofuranosidase activity and high transferase activity, and is capable of efficiently producing fructooligosaccharides.

&bgr;-fructofuranosidase and gene thereof

A novel &bgr;-fructofuranosidase gene and a &bgr;-fructofuranosidase encoded by the gene, a process for isolating a &bgr;-fructofuranosidase gene using the novel &bgr;-fructofuranosidase gene, and a novel &bgr;-fructofuranosidase obtained by this isolation process are disclosed. A novel mold fungus having no &bgr;-fructofuranosidase activity suitable for the production of &bgr;-fructofuranosidase, and a system for producing a recombinant &bgr;-fructofuranosidase using the novel mold fungus as a host is disclosed. Further, a &bgr;-fructofuranosidase variant which selectively and efficiently produces a specific fructooligosaccharide such as 1-kestose from sucrose is disclosed.

&bgr;-fructofuranosidase and its gene, method of isolating &bgr;-fructofuranosidase gene, system for producing &bgr;-fructofuranosidase, and &bgr;-fructofuranosidase variant

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Saitama, Japan

Akitaka Nakane