Jxtg Nippon Oil & Energy Corporation

Astellas Pharma Gmbh

Eneos Corporation

Nippon Oil Company

Jx Nippon Oil Energy Corporation

Hitachi, Ltd.

Mitsubishi Heavy Industries Limited

Victor Company of Japan, Limited

Nippon Oil Corporation

Nippon Mitsubishi Oil Corporation

Momentive Performance Materials Japan LLC

Kabushiki Kaisha Csk

Ge Toshiba Silicones Co., Ltd.

Akira Takagi

Go Tatsumi

Shozo Hayashi

Noriko Ayame

Yasuo Togami

Shingo Matsuki

Takatsune Yoshida

Yoshiaki Umemoto

Sachie Namiki

Takuya Matsumoto

Hiroshi Suzuki

Hiroyuki Kojima

Suzushi Nishimura

Shigeki Matsui

Kazuo Tagawa

Shinichi Komatsu

Yoshihiro Kobori

Yosuke Numao

Shinichiro Suzuki

Tadahiro Kaminade

Ryuichi Ueno

Kikuo Mochizuki

Takayuki Hirayama

Toshiro Sakai

Noboru Yamashita

Shinsuke Oba

Hiroya Miyamoto

Toshikatsu Shoko

Motonobu Saito

Hiromitsu Matsuda

Hajime Aoki

Kouhei Yamashita

Shinichi Higashi

Ryo Kojima

Masato Sone

Yukinobu Harada

Tatsnobu Yoshioka

Ken Shimada

Minoru Yukawa

Jun Takada

Shin-ichi Komatsu

Katsumi Saito

Maeda Atsushi

A defoaming agent obtainable by a process that includes: polymerizing (A) at least one polymerizable monomer in a composition, the composition comprising (C) a solvent and (B) at least one non-polymerizable polysiloxane dissolved in the (C) solvent, wherein the component (A) optionally comprises at least one Si-atom-containing monomer in an amount of less than 10 mass % on the basis of the total mass of the component (A).

Defoaming agent and lubricating oil composition

Provided is a pharmaceutical composition for oral administration in which the solubility and/or dissolution properties of enzalutamide are improved and supersaturation is maintained. Also provided is a pharmaceutical composition for oral administration in which the oral absorbability of enzalutamide is improved. The pharmaceutical composition for oral administration comprises enzalutamide and polyvinyl alcohol.

Pharmaceutical composition for oral administration comprising enzalutamide

A lubricating oil composition including: a lubricating base oil; (A) a first defoaming agent, the first defoaming agent being (A1) a first polymer, or (A2) a second polymer, or any combination thereof; and (B) a second defoaming agent, the second defoaming agent being a silicone defoaming agent, the (A1) first polymer including: a first polymer chain including a polysiloxane structure, the polysiloxane structure having a polymerization degree of 5 to 2000 and being represented by the following general formula (1); and a second polymer chain bonded with the first polymer chain, the second polymer chain including a repeating unit represented by the following general formula (2), the (A2) second polymer being a copolymer of a first monomer component and a second monomer component, the first monomer component represented by the general formula (7) or (8), the second monomer component represented by the general formula (9).

Lubricating oil composition and method for defoaming lubricating oil, and defoaming agent composition

A data management device is communicably connected to a first database and a second database in a different structure from the first database. The second database is converted to the structure of the first database, and is stored as a conversion table based on first data schema information defining the structure of the first database and second data schema information defining the structure of the second database. For which database a query that is received from the outside and described corresponding to the structure of the first database is a query is determined with reference to the conversion table. When the query is determined to be a query for the second database, the query is converted and is introduced into the second database, and a query result in response to the query is converted into a format corresponding to the structure of the first database and output.

Data management device and data management method

Provided is a pharmaceutical composition in which the solubility and/or dissolution properties of a poorly-soluble drug can be improved. The pharmaceutical composition comprises a poorly-soluble drug, and polyvinyl alcohol having a saponification degree of 63 mol % or more and 67 mol % or less.

Pharmaceutical composition

A defoaming agent including a polymer, the polymer including: at least one first polymer chain including a polysiloxane structure represented by the following general formula (1); and at least one second polymer chain including a repeating unit represented by the following general formula (2) and bonded to the first polymer chain: wherein in the formula (1), repeating units may be in any order; each of Rand Ris independently a Corganic group comprising no fluorine atom; at least one of Rand Ris the organic group comprising no less than 3 fluorine atoms; m is an integer of no less than 1; and n+m is 5 to 2000, wherein in the formula (2), Xis a repeating unit obtainable by polymerization of an ethylenic unsaturated group; Yis a substituted or unsubstituted Chydrocarbyl group; and Zis a linking group linking Xand Y.

A defoaming agent obtainable by a process, the process including the step of: (i) polymerizing (B) at least one defoaming agent monomer in (A) a polymerization solvent under coexistence of (C) a polymer soluble in the polymerization solvent.

A lubricating oil composition including: a lubricant base oil; (A) a first defoaming agent obtainable by a process, the process including the step of: polymerizing (b) at least one defoaming agent monomer in (a) a polymerization solvent under coexistence of (c) a polymer soluble in the polymerization solvent; and (B) a second defoaming agent being a silicone defoaming agent.

Lubricating oil composition, method for defoaming lubricating oil, and defoaming agent composition

A defoaming agent including a polymer, the polymer including a repeating unit represented by the following general formula (1); and a repeating unit represented by the following general formula (3): wherein in the general formula (1), Xis a repeating unit obtainable by polymerization of a first ethylenic unsaturated group; Yis a side chain including a linear or branched polysiloxane structure, the polysiloxane structure having a polymerization degree of 5 to 300; and Zis a linking group linking the repeating unit Xand the side chain Y; wherein in the general formula (3), Xis a repeating unit obtainable by polymerization of a second ethylenic unsaturated group, Yis a Chydrocarbyl side chain; and Zis a linking group linking the repeating unit Xand the side chain Y.

A defoaming agent comprising: a polymer comprising a repeating unit represented by the following general formula (1): where in the general formula (1), Xis a repeating unit obtainable by polymerization of an ethylenic unsaturated group; Yis a side chain comprising a linear or branched polysiloxane structure, the polysiloxane structure comprising a repeating unit represented by the following general formula (2) and having a polymerization degree of 5 to 300; and Zis a linking group linking the repeating unit Xand the side chain Y; wherein in the general formula (2), Rand Rare each independently an organic group having a carbon number of 1 to 18.

The present invention provides a poly(meth)acrylate-based viscosity index improver comprising a core portion and three or more arm portions, wherein each of the arm portions consists of a polymer chain comprising a structural unit represented by the following formula (1), and one end of the polymer chain is bonded to the core portion, and wherein a weight-average molecular weight Mw is 100000 or more, and a ratio of the weight-average molecular weight Mw to a number average molecular weight Mn, Mw/Mn, is 1.6 or less.  [Rrepresents hydrogen or a methyl group, and Rrepresents a C1 to C36 alkyl group.]

Poly(meth)acrylate-based viscosity index improver, lubricant additive and lubricant composition containing viscosity index improver

The silicone composition for sealing a semiconductor, comprises: (A) 100 parts of a polyorganosiloxane having one or more alkenyl groups, obtained by reacting (a1) 60 to 99 parts of an organosiloxane containing at least a trifunctional siloxane unit not taking part in a hydrosilylation reaction, with (a2) 40 to 1 parts of an organosiloxane containing a bifunctional siloxane unit having an alkenyl group and/or a monofunctional siloxane unit having an alkenyl group; (B) an amount of a polyorganohydrogensiloxane having two or more hydrogen atoms having a viscosity at 25&#xb0; C. of 1 to 1000 mPa&#xb7;s so that an amount of the hydrogen atoms is 0.5 to 3.0 mol per mol of the alkenyl groups; and (C) a platinum-based catalysts, wherein a decrease in storage modulus of a cured product thereof from 25&#xb0; C. to 50&#xb0; C. is 40% or more. Specifically the polyorganosiloxane (A) is prepared by block or graft polymerization and equilibration reaction of three specific, different, organosiloxanes including a branched siloxane, a linear siloxane and a cyclic siloxane.

Silicone composition for sealing semiconductor

A method for controlling a particle diameter and a particle diameter distribution of emulsion particles during manufacturing of an emulsion dispersion is provided. The method includes causing two or more types of liquids substantially immiscible with each other to continuously and sequentially pass through net bodies. The net bodies are disposed in a cylindrical flow passage at intervals of 5 to 200 mm, and the number of the net bodies is more than 50 and 200 or less. Each of the net bodies is equivalent to a gauze having a mesh number of 35 mesh to 4000 mesh in accordance with an ASTM standard and has a surface that intersects the direction of the flow passage. An emulsification apparatus used for the method includes a feed pump for feeding two or more types of liquids substantially immiscible with each other; and a cylindrical flow passage to which the two or more types of liquids fed by the feed pump are delivered. A predetermined number of net bodies are disposed in the cylindrical flow passage at predetermined intervals, and each net body has a surface intersecting the direction of the flow passage.

Method and apparatus for controlling particle diameter and particle diameter distribution of emulsion particles in emulsion

The present invention relates to an emulsification method and an emulsification apparatus, capable of attaining easy control of particle size and particle size distribution, and simple scale-up and maintenance, and providing an emulsifying amount sufficient for industrial production. Namely, the method comprises continuously and successively passing two or more types of liquids which are substantially immiscible with each other through two or more mesh members disposed at certain intervals in the presence of an emulsifier to thereby perform emulsification, and the emulsification apparatus as an apparatus for carrying out the method comprises liquid feed pumps for feeding two or more types of liquids which are substantially immiscible with each other, and a cylindrical flow passage to which the two or more types of liquids are fed by the liquid feed pumps, the cylindrical flow passage including a predetermined number of wire gauzes disposed therein at a predetermined interval.

Continuous emulsification method and emulsification apparatus therefor

The present invention relates to conjugates of a lipid, substrate peptide of an enzyme secreted from the cells of mammals, including humans, and a water-soluble polymer that can be used as colloidal carriers and the like of tissue-specific drug delivery systems, methods of producing these conjugates, peptide-water-soluble polymer conjugates optionally having protective groups that are useful as the intermediates of these conjugates, colloidal carriers made from these conjugates, and tissue-specific drug delivery systems that use these colloidal carriers.

Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems

Growing community of inventors

Tokyo, Japan

Akira Takagi