Arkray, Inc.

Sekisui Medical Co., Ltd.

Akira Sezaki

Takeshi Takagi

Toshikatsu Sakai

Tokuo Kasai

Koji Sugiyama

Takanori Kamada

Yoshikiyo Hongo

Takuya Yotani

Takayuki Oka

Seiji Satake

Takeshi Matsubara

Makoto Takahara

Hajime Fukumaru

Takafumi Aono

A liquid chromatography measurement method includes: switching between a first measurement mode using a liquid chromatography method in which hemoglobin A1c and a hemoglobin variant are measured in a measurement sample by sequentially delivering a first component-separating eluent, a second component-separating eluent and a wash eluent to an analytical column, and a second measurement mode using the liquid chromatography method in which the hemoglobin A1c is measured by sequentially delivering the first component-separating eluent and the wash eluent to the analytical column; delivering the wash eluent in the first measurement mode prior to an influence from the second component-separating eluent disappearing such that a first retention time of the hemoglobin A1c in the first measurement mode and a second retention time of the hemoglobin A1c in the second measurement mode are substantially the same as each other; and delivering the first component-separating eluent after the wash eluent.

Liquid chromatography measurement method, liquid chromatography measurement instrument, and liquid chromatography measurement program storage medium

A channel bubble reduction device includes a liquid accommodation portion, that accommodates a liquid, a liquid supply apparatus that, with a pushing operation of a rod, discharges the liquid through an aperture portion of a tube portion, a first channel that connects the aperture portion of the liquid supply apparatus with the liquid accommodation portion, and an air layer formation apparatus that forms an air layer in at least one of the first channel or the tube portion.

Channel bubble reduction device, channel bubble reduction method, and chromatography device

A liquid chromatography apparatus is provided with a sample preparation unit, a column that separates components of a sample, an eluent supplier that includes a feeder for supplying eluents to the column, a flow path directional valve capable of introducing fixed amounts of the sample and the eluents to the column, an analyzer for analyzing a test solution composed of the sample components separated by the column and one of the eluents, and a controller, wherein the eluent supplier supplies the eluents to the flow path directional valve in an unmixed state. As a result of employing this configuration, analysis time is shortened and eluent consumption is reduced.

Liquid chromatography apparatus and liquid chromatography

A bubble reduction device, chromatography device, bubble reduction method and bubble reduction program capable of reducing bubbles in an eluent. Included are a liquid accommodation portion, a liquid supply apparatus, an air layer formation apparatus, a first channel and an evacuation portion. The liquid accommodation portion accommodates a liquid that is to elute an analysis component from a specimen adsorbed to an adsorption portion. The liquid supply apparatus, by operation of a rod pushing up and polling down, sucks and discharges the liquid through an aperture portion of a tube portion, the aperture portion being oriented upward. The air layer formation apparatus forms an air layer in the tube portion. The first channel connects the liquid supply apparatus with the liquid accommodation portion. The evacuation portion is connected to the first channel via a first switching valve and evacuates the air layer through the first channel.

Bubble reduction device, chromatography device, bubble reduction method, and bubble reduction program

An analyzing device includes a feeder connected to a container in which a sample is contained for sucking the sample from the container and feeding the sample, and a controller for performing control for feeding from the feeder to a measurer. In measuring the sample, the controller performs control so that results of a plurality of times of measurement are obtained with respect to the single container in which the sample is contained, without changing the container. This arrangement allows quick accuracy check.

Analyzing device and method for controlling same

The present invention relates to a deaeratorincluding: a liquid flow space; reduced-pressure spacesA,B, andC; gas permeable filmsA,B, andC that separate these spaces; and a pump for discharging gas from within the reduced-pressure spacesA,B, andC to the outside, and to a liquid chromatograph equipped with the deaerator. The deaeratorfurther includes gas partial pressure variation suppression meansA,B,C,Ab,Bb,Cb,A,B, andC for suppressing variations in partial pressures of a specific gas in the reduced-pressure spacesA,B, andC.

Degasifier and liquid chromatograph equipped therewith

The present invention relates to a liquid chromatography apparatus X, which is provided with a deaerator. The liquid chromatography apparatus X is further provided with a dissolved oxygen density adjusting means for maintaining a density of dissolved oxygen in an eluting solution to be supplied to a columnconstant. Preferably, the dissolved oxygen density adjusting means is configured so as to adjust the density of the dissolved oxygen in the eluting solution by adjusting a degree of decompression in a decompression space of the deaeratorbased on a measurement result by temperature measurement meansA,B, andC for measuring the temperature of the eluting solution.

Growing community of inventors

Kyoto, Japan

Akira Sezaki