Omron Corporation

Kyoto University

Megakaryon Corporation

Akira Ota

Masanori Nakamura

Yojiro Saruwatari

Tatsuo Shinoura

Koji Eto

Yukitaka Ito

Hideya Seo

Yasuko Hazama

The present invention provides a method for screening for platelet production promoters, the method including a step for selecting a candidate substance that significantly increases expression of TUBB1 as a platelet production promoter.

Method for screening for platelet production promoters

The present invention provides: a platelet production promoter that contains one or more substances selected from the group consisting of Wnt inhibitors and FMS-like tyrosine kinase (FLT) inhibitors; and a platelet production method that uses this platelet production promoter.

Platelet production promoter and method of producing platelets using same

A relay includes a permanent magnet and a magnetic circuit. The permanent magnet is disposed between a pair of electromagnets. The pair of the electromagnets is formed by winding coils around body portions of spools. Each spool has flanges integrally formed on both upper and lower end portions thereof. The magnetic circuit is formed by a yoke spanning the spools and the permanent magnet. The permanent magnet is held by the upper and lower flanges of a pair of the spools that are juxtaposed.

Relay

A relay includes a contact point block having a support shaft with both ends spanning a contact point base, a plunger having a movable contact at a lower end thereof, and a movable iron piece configured to drive the plunger and to have a plate spring. The relay also includes an electromagnetic unit and a base block having a fixed contact point at a position opposite to the movable contact point. The movable iron piece is supported on the supporting shaft. The plunger is inserted through an operation hole of the contact point base. Upper and lower surfaces of the contact point block are held by the electromagnetic unit and the base block. The electromagnetic unit directly fixes the iron core to an upper surface of the contact point base.

A relay driving a plunger includes a movable iron piece, and a movable contact point, and position restricting means. The movable iron piece is configured to rotate around a horizontal shaft center between a contact point base and an electromagnetic unit based on excitation and nonexcitation of an electromagnetic unit placed above the contact point base. The movable contact point is fixed to a lower end portion of the plunger protruding from a lower surface of the contact point base. The movable contact point is contacted with and separated from a fixed contact point. The position restricting means is provided on an upper surface side of the contact point base.

A relay includes a movable iron piece, a plate spring fixed to the one surface of the movable iron piece, a shaft hole formed by the one surface of the movable iron piece and the plate spring, and a supporting shaft inserted through the shaft hole. The movable iron piece is rotated round the supporting shaft based on excitation and nonexcitation of a magnetic unit. Both end portions of the plate spring alternately drive a contact point unit. The shaft hole is formed by a flat portion of the one surface of the movable iron piece and a bearing portion formed by subjecting the plate spring to bending work. The movable iron piece is supported so as to be rotatable.

Growing community of inventors

Kyoto, Japan

Akira Ota