Banyu Pharmaceutical Co. Ltd

Akira Okura

Hiroyuki Suda

Masanori Okanishi

Kenji Kawamura

Katuhisa Kojiri

Seiichi Tanaka

Katsuhisa Kojiri

Daisuke Uemura

Kohtaro Funaishi

Koutaro Funaishi

This invention relates to 12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione derivatives represented by the following general formula, pharmaceutically acceptable salts thereof, a method for preparation thereof and a use thereof: ##STR1## [wherein R.sup.1 denotes a monosaccharide group having 5 to 7 carbon atoms, and the hydroxyl groups of this monosaccharide group can be replaced by the same or different 1 to 3 groups selected from the group consisting of a hydrogen atom, lower alkyl group, lower alkylcarbonyloxy group and lower alkoxy group.]

Method for preparing antitumor substance BE-13793C derivatives

Antitumor substance BE-13793C derivatives

A novel antitumor substance BE-13793C or a pharmaceutically acceptable salt thereof, which is represented by the following formula: ##STR1## an anticancer agent comprising the novel substance or a pharmaceutically acceptable salt thereof, a method of producing the novel substance and a microorganism Streptoverticillium FERM P-10489, capable of producing the novel substance are disclosed.

Streptoverticillium ferm P-10489 which produces antitumor agent BE-13793C

A novel antitumor substance BE-13793C or a pharmaceutically acceptable salt thereof, which is represented by the following formula: ##STR1## an anticancer agent comprising the novel substance or a pharmaceutically acceptable salt thereof, a method of producing the novel substance and a microorganism capable of producing the novel substance are disclosed.

Antitumor substance BE-13793C

An antitumor substance BE-12406 or a pharmaceutically acceptable salt thereof, which is represented by the general formula ##STR1## and a method of producing the novel substance.

Antitumor substance BE-12406

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Tokyo, Japan

Akira Okura