Other

Astellas Pharma Gmbh

Nagase Co., Ltd.

Akira Nakagawa

Kouichi Tanaka

Koji Nagai

Kunio Kosaka

Toshitsugu Miyazaki

Nakako Arao

Senji Takahashi

Yuuko Osanai

Tatsuya Matsuda

There are provided a novel microorganismsp. B20 strain which produces (E)-4-(2-isocyanovinyl)phenyl &#x3b1;-rhamnopyranoside having a favorable effect of inhibiting melanogenesis and &#x3b1;-L-rhamnopyranoside produced thereby. This novel microorganism is a gram-negative bacillus isolated from soil and shows motility owing to polar flagellum. The &#x3b1;-L-rhamnopyranoside, which is produced by culturing the microorganism under aerobic conditions at a culture temperature of 10 to 37&#xb0; C. and at a medium pH of about 5 to 9 usually for about 1 to 7 days, is useful as a highly safe and stable whitening agent.

Microorganism, its product and utilization thereof

A hose coupler particularly suitable for spiral wire reinforced hoses having either one or both of their outside and inside surfaces embossed by the spiral reinforcement of metal or synthetic resin material provided either externally wound about the outside or internally imbedded between the two pliers along the entire hose length, is disclosed, which has a cylindrical sleeve for enclosing the engaged end of the hose about the nipple. This sleeve is itself encased within the back nut, when it is engaged with the main body. An annular projection is formed in the inside of the sleeve at its one end, which is provided to be pressed against the outside of the hose over a longitudinal range that is not less than the pitch of the reinforcement helix in the hose. A tubular seal is provided wound about the outside of the nipple at its forward end. The tubular seal is formed to have its longitudinal length to match the dimension of the contacted surface of the projection. Also, the tubular seal is situated in the nipple circumference at such a point that, when the back nut is engaged with the main body, with the hose end being pulled up into place over the nipple within the sleeve, the projection is pressed against the hose just over the seal. In this way, the hose is sealed all way round its circumference on both of the knaggy outside and inside.

Hose coupler for spiral wire reinforced hoses

20-Amino derivatives of tylosin and desmycosin are active against bacteria and Mycoplasma.

20-Amino tylosin derivatives and pharmaceutical compositions containing

Growing community of inventors

Fuchu-shi, Tokyo, Japan

Akira Nakagawa