Shionogi Company Limited

Akira Murabayashi

Yasuo Makisumi

Hideyuki Takenaka

Hiroyuki Kai

Akira Takase

Toshio Takahashi

Takashi Sasatani

Katsuya Tawara

Yoshihachi Watanabe

Michio Masuko

Kazuo Ueda

Shinzaburo Sumimoto

Ichiro Ishizuka

Takao Konishi

Takeo Ishiguro

Akira Ino

Takayuki Hatta

Process for producing alkoxyiminoacetamide derivatives

2-(substituted phenyl)-2-alkoxyimino-N-alkylacetamide compounds and

There is disclosed an efficient process for producing .alpha.-ketoacetamide of the formula: ##STR1## which is useful as an intermediate for the production of various alkoxyiminoacetamide compounds to be used for agricultural fungicides. In this process, a corresponding acid halide is condensed with isocyanide to produce the .alpha.-ketoacetamide.

Process for producing alpha-ketoamide derivative

There is disclosed an efficient process for producing .alpha.-ketoacetamide of the formula: ##STR1## which is useful as an intermediate for the production of various alkoxyiminoacetamide compounds to be used for agricultural fungicides. In this process, a corresponding acid halide is condensed with isocyanide to produced the .alpha.-ketoacetamide.

Process for producing .alpha.-ketoamide derivative

Novel 1-substituted -2-imidazolyl (or 1,2,3-triazolyl)cyclohexanols or cycloheptanols having anti-fungal activity against wide range of agricultural fungi with vapor effect.

Azolyl cycloalkanol derivatives and agricultural fungicides

New (2-propynylamino)isoxazole and (3-iodo-2-propynylamino)isoxazole derivatives having anti-microbial activity which are used as active ingredients in anti-microbial compositions for medical use, for agricultural use and also for veterinary use.

Iodo propargylaminoisoxazoles as fungicides

New 2-(2-propynylamino)thiazole and 2-(3-iodo-2-propynylamino)thiazole derivatives having anti-microbial activity which are used as an active ingredient in anti-microbial compositions for medical and agricultural use.

Propynylaminothiazole derivatives

3-Amino-5-t-butylisoxazole is prepared by reacting pivaloylacetonitrile with hydroxylamine in aqueous medium under basic conditions and treating the reaction products with an acid. The process is economical and industrial.

Process for the production of 3-amino-5-t-butylisoxazole

3-Aminoisoxazoles of the formula: ##STR1## (wherein R is C.sub.1 -C.sub.6 alkyl, phenyl or halo-phenyl) are prepared by reacting a .beta.-ketonitrile of the formula:

Process for the production of 3-aminoisoxazoles

Urea derivatives of the formula ##STR1## (wherein Ar represents a residue of 5- or 6-membered heteroaromatic ring; R represents a hydrogen atom or a C.sub.1 -C.sub.6 alkyl group; R.sup.1 represents a C.sub.1 -C.sub.6 alkyl group; and R.sup.2 represents a C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, or C.sub.1 -C.sub.6 alkoxy group) are produced by reacting an amine of the formula

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Ibaraki, Japan

Akira Murabayashi