Mie University

Akira Mizoguchi

Koji Tanaka

Kazushi Kimura

Kousyoku Sai

Shujie Wang

Kyosuke Tanaka

Aika Kaito

Tetsuya Nosaka

Yuji Toiyama

Naoyuki Katayama

Hidemasa Goto

Takeshi Fujiwara

Yuuhei Nishimura

Masahiko Sugimoto

Provided is a vital stain inspection method for distinguishing between cancer cells and normal cells within a lumen, or on the serous membrane side of an organ, by means of laser irradiation after organ tissue has been stained by curcumin, Red #3 or Red #106, which are edible color dyes.

Detection method

A cancer test device () is provided with: an application unit () for applying a staining agent (), which can selectively stain a product of a cancer-relating gene in a living cell a chromatic color, onto a group of living cells; an imaging unit () for imaging the group of living cells having the staining agent () applied thereto; and a determination unit () for determining the level of malignancy of cancerization of the group of living cells on the basis of the state of the stained expression pattern of the cancer-relating gene in the group of living cells in an image obtained by the aforementioned imaging.

Cancer test device, cancer test method, and staining agent for use in cancer test

A vital stain for observation under multiphoton laser microscopy, the vital stain comprising one or more edible dye compounds.

Vital stain

The present invention is provided with an imaging unit () that has an imaging head () to be inserted into the digestive tract () and images a living body by applying a laser to the digestive tract () via the imaging head (); a control unit () for controlling the imaging head () to move inside the digestive tract (); and an image processing unit () for processing an image captured by the imaging unit (). The imaging unit () captures a plurality of imaging regions (P) to be imaged along with the movement of the imaging head () such that a portion of adjacent imaging regions (P, P) overlap, and the image processing unit () overlaps regions (Pa) in which the plurality of imaging regions (P, P) are overlapped to generate a composite image.

Laser endoscope device

Growing community of inventors

Mia, Japan

Akira Mizoguchi