Ajinomoto Co., Ltd.

Renesas Electronics Corporation

Akira Imaizumi

Toshihiko Ando

Naoyuki Okamoto

Takayuki Tanaka

Kazuhiko Matsui

Yuki Miyazawa

Kazuki Nakagawa

Takeshi Fujieda

Takashi Mikami

Mina Nakamura

Hiroshi Matsumoto

Hiroshi Yamamoto

Hiroyuki Kojima

Yoshihiro Usuda

Vera Georgievna Doroshenko

Takeshi Miura

Shintaro Iwatani

Noriko Takahashi

Larisa Gotlibovna Airikh

Nobukazu Ono

Masahiko Higashiyama

Yohei Miyagi

Takahiko Muramatsu

Shoji Tsuchioka

Akio Shibuya

Katsuyoshi Tsuchiya

Irina Sergeevna Tsyrenzhapova

Yukiko Ishikawa

Ryosei Sakai

Fumio Imamura

An evaluating method includes an evaluating step of evaluating a state of ketosis in postpartum dairy cows for a dairy cow using at least one value of concentration values of Ala, Arg, Asn, Asp, BCAA, Cit, Cys, Glu, Gln, Gly, His, Ile, Leu, Lys, Met, 3MeHis, Orn, Phe, Pro, Ser, Tau, Thr, Trp, Tyr, and Val and concentration values of ALB, ALT, AST, BHBA, BUN, Ca, gGTP, Glc, NEFA, T-Bil, TCHO, TG, and TP in blood of the dairy cow before parturition.

Evaluating method of ketosis in postpartum dairy cows

According to the method of evaluating lung cancer, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a lung cancer state in the subject is evaluated based on the concentration value of at least one of Orn, Lys, ABA, Arg, Glu, His, Tau, Pro, Ala, Cit and Ile contained in the measured amino acid concentration data of the subject.

Lung cancer evaluating apparatus, method, system, and program and recording medium therefor

An L-amino acid is produced by culturing a microorganism of the family Enterobacteriaceae which has the ability to produce an L-amino acid and which has been modified so as to increase the expression of the evgA gene, the gadE gene, and/or the ydeO gene. These genes encode a transcription factor involved in the EvgAS two-component system regulon. The culture takes place in a medium, and the L-amino acid is collected from the medium or cells.

L-amino acid-producing bacterium and a method for producing an L-amino acid

According to the method of evaluating colorectal cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a colorectal cancer state in the subject is evaluated based on the concentration value of at least one of Arg, Cys, Orn, Trp, Glu, ABA, Val, Phe, Leu, Gln, Ile and His contained in the measured amino acid concentration data of the subject.

Method, apparatus, system, program, and computer-readable recording medium for evaluating colorectal cancer

According to the method of evaluating prostatic disease of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of prostatic disease including at least one of prostatic cancer and prostatic hypertrophy in the subject is evaluated based on the concentration value of at least one of Tau, Thr, Ser, Asn, Glu, Pro, Gly, Ala, Cit, ABA, Val, Met, Ile, Leu, Phe, His, Trp, Orn, Lys, and Cys2 contained in the measured amino acid concentration data of the subject.

Method of evaluating prostatic disease

According to the method of evaluating breast cancer of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a breast cancer state in the subject is evaluated based on the concentration value of at least one of Ser, Gln, Val, Cys, Orn, Arg, Ile and ABA contained in the measured amino acid concentration data of the subject.

Method of evaluating breast cancer, breast cancer-evaluating apparatus, breast cancer-evaluating method, breast cancer-evaluating system, breast cancer-evaluating program and recording medium

An electrical characteristics test for a semiconductor integrated circuit using a Kelvin contact method can be conducted in a pre-process without obstructing the reduction in size of a semiconductor chip or without complicating the circuit design. A probe card in a testing apparatus includes probes for Kelvin contact, the probes for Kelvin contact including a coil probe and a POGO pin probe disposed inside the coil probe, and a probe for two-terminal measurement. Electrode pads formed in each chip area over a wafer are in a relation of A=B&#x3c;2A, given that the area of one of the electrode pads with which the probe for Kelvin contact comes into contact is B and the area of the other electrode pad with which the probe for two-terminal measurement comes into contact is A.

Semiconductor device and method for manufacturing the same

A method is provided for producing an L-amino acid by culturing a microorganism belonging to the Enterobacteriaceae family and having the ability to produce an L-amino acid, in a medium to produce and accumulate the L-amino acid in the medium. The microorganism has been modified by introduction of a DNA fragment which includes a pho regulon promoter and a structural gene encoding an L-amino acid biosynthetic enzyme, which is ligated downstream of the promoter so that the gene is expressed by the promoter, and so that the activity of the L-amino acid biosynthetic enzyme is increased by the expression of the gene by the promoter. In this way, the L-amino acid that is produced in the medium can be collected. Furthermore, the phosphorus concentration in the medium is such that the expression of the gene by the promoter is induced.

Method for production of an L-amino acid

In a method for producing a target substance utilizing a microorganism, which comprises culturing a &#x3b3;-proteobacterium in a medium to produce and accumulate the target substance in the medium or cells and collecting the target substance, there is used a strain in which the ArcA protein does not normally function in the cell by means of, for example, disruption of the arcA gene on the chromosome.

Method for producing target substance by fermentation

Growing community of inventors

Kawasaki, Japan

Akira Imaizumi