Kureha Kagaku Kogyo Kabushiki Kaisha

Akira Iizuka

Takashi Yamauchi

Yutaka Konai

Shoichiro Hayashi

Masaaki Takahashi

Yoshiro Kobayashi

Kiro Asano

Itsumaro Kumadaki

Disclosed herein are the novel 6-substituted naphthalene-2-carboxylic acids represented by the formula (I): ##STR1## wherein X represents a hydroperoxy group or a hydroxy group, and a process for producing the 6-substituted naphthalene-2-carboxylic acid represented by the formula (I) by reacting 6-isopropylnaphthalene-2-carboxylic acid with molecular oxygen under heating in the presence of a salt of persulfuric acid as a catalyst in an aqueous alkaline solution.

6-substituted naphthalene-2-carboxylic acids and process for producing

Disclosed herein are methyl 2-(2-hydroperoxy-2-propyl)naphthalene-6-carboxylate represented by the formula (I): ##STR1## and a process for producing the compound represented by the formula (I) at a high purity and in a high yield.

Methyl 2-(2-hydroperoxy-2-propyl)naphthalene-6-carboxylate and process

A novel compound of 2-[para-(2-substituted or unsubstituted-3,3,3-trifluoropropyl)phenyl]propionic acid or a salt thereof which has a specific pharmacological activity and a pharmaceutical composition comprising the novel compound as an active ingredient are disclosed.

2-[Para-(2-substituted or

Disclosed is a method for producing trans-4-aminomethyl cyclohexane-1-carboxylic acid by heating and isomerizing cis-4-aminoethyl cyclohexane-1-carboxylic acid hydrochloride or a mixture of cis-4-aminomethyl cyclohexane-1-carboxylic acid hydrochloride with trans-4-aminomethyl cyclohexane-1-carboxylic acid hydrochloride in an atmosphere of hydrogen chloride gas and in the absence of a solvent.

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Iwaki, Japan

Akira Iizuka