Other

The Nisshin Oil Mills, Ltd.

Wako Pure Chemical Industries, Inc.

The Johns Hopkins University

Japan Tobacco Inc.

Nippon Shinyaku Company, Ltd.

University of California

Takeda Chemical Industries, Inc.

Toyota Boshoku Kabushiki Kaisha

The Japan Steel Works, Ltd.

Kanebo, Limited

Sanwa Kagaku Kenkyusho Co., Ltd.

Daiichi Seiyaku Co., Ltd.

Toho Yakuhin Kogyo Kabushiki Kaisha

Akira Hasegawa

Makoto Kiso

Tomio Ishida

Yoshiaki Yoshikuni

Ichiro Azuma

Yuichi Yamamura

Ronald L Schnaar

Lynda J Yang

Shinichi Uesato

Hiroshi Ueda

Takeaki Nakamura

Yasuo Suzuki

Masanao Murata

Takahiko Mitani

Tsutomu Yamamoto

Shinji Satomura

Toshinao Usui

Yutaka Saito

Takahito Jomori

Takuji Kakigami

Shoji Yokochi

Masayuki Tobo

Kazuyuki Morihara

Shigeru Kobayashi

Masanobu Suzuki

Akira Tashita

Haruo Oguchi

Hideharu Ishida

Stephan Ladisch

Kenichi Kikuchi

Yoshiro Ishiwatari

Hitoshi Hamashima

Hajime Yasui

Takao Igami

Kouji Kanbara

Yoshikazu Tojo

Shinichiro Hattori

Takashi Tsukaya

Yoshihito Shimizu

Tatsuya Yamaguchi

Kazunari Kobayashi

Makato Kiso

Seiichi Kitamura

Yukihiro Isogai

A gas turbine system comprises an alarm signal calculation circuit, a shutdown calculation circuit and a flashback-error signal prevention calculation circuit. The alarm signal calculation circuit, the shutdown calculation circuit and the flashback-error signal prevention calculation circuit are integrated in a combustion monitoring device for monitoring combustion condition of combustion gas in a gas turbine-combustor.

Gas turbine system

Compounds which can stimulate neuronal growth by inhibiting the neuronal inhibitory activity of myelin-associated glycoprotein (MAG), and a method of using the compounds for stimulating neuronal growth are provided. The invention further provides a method of identifying compounds which inhibit myelin-associated glycoprotein inhibition of axonal outgrowth of injured nerve cells. The method involves contacting the compound with myelin-associated glycoprotein under conditions which allow myelin-associated glycoprotein and the compound to bind and detecting the binding.

Compounds for stimulating nerve growth

There are described sulfated and phosphated saccharide erivatives of the Formula ##STR1## wherein R.sub.1 is hydrogen atom or a residue of sulfate, phosphate or L-fucose; R.sub.2, R.sub.3 and R.sub.4 are hydrogen atom or a residue of sulfate or phosphate, respectively; 1 is an integer of 0 or 1;

Sulfated and phosphated saccharide derivatives, process for the

The invention provides important intermediate compounds for the synthesis of acidic glycolipids which are identical with the glycolipid antigens isolated from the acidic glycolipid fractions of peripheral nerve and embryonic central nervous system and preparation methods thereof. By the adoption of the present intermediate compounds, sulfation of 3-hydroxyl group of end glucuronic acid portion of the acidic glycolipid can be quite easily carried out and total synthetic yield be greatly improved.

Intermediate compounds for the synthesis of glycolipids

Moranoline derivative

Novel glycolipid derivatives of Formula (I): ##STR1## wherein R is a long chain alkyl, or their salts are disclosed. These compounds act as a ligand for selectin family and exhibit a remarkable inhibitory effect on the binding of selectin family to its native ligand sialyl Lewis.sup.x.

Glycolipid derivatives acting as ligands for selectins

Synthetic compounds which are useful for suppressing an immune response are disclosed. The synthetic compounds have the formula ##STR1## wherein A is a carbohydrate moiety which corresponds to the carbohydrate moiety of a naturally occurring ganglioside, n is 5 to 20 and m is to 20. Also presented are methods for suppressing an immune response in an animal and compositions of matter employing the compounds as shown above.

Synthetic ganglioside derivatives

Lewis-type sugar chain derivative

Disclosed are ganglioside GM.sub.3 analogs represented by the formula ##STR1## in which X represents a radical of the following formula ##STR2## wherein at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is hydrogen and the remainder is hydroxyl; ##STR3## wherein at least one of R.sub.5 and R.sub.6 is hydrogen and the remainder is methyl; ##STR4## wherein m is an integer of 15 to 25, l is an integer of 0 to 3, n is an integer of 11 to 15 and Ac represents acetyl. The ganglioside GM.sub.3 analogs are expected to possess an inhibitory activity for influenza virus.

Ganglioside GM3 analogs

Disclosed are thioglycoside analogs of gangliosides represented by the formula ##STR1## in which Y represents a radical of the following formula ##STR2## and X represents a radical of the formula ##STR3## wherein m is an integer of 15 to 25, l is an integer of 0 to 3 and n is an integer of 11 to 15. The thioglycoside analogs are expected to exert specific enzyme-inhibitory effects.

Thioglycoside analogs of gangliosides

An improved process for the preparation of O-glycosyl compounds of sialic acid, which are useful as intermediates in the synthesis of sialoconjugated glycosides. This process comprises effecting condensation reaction between thioglycosides of sialic acid and sugar derivatives in the presence of N-iodosuccinimide and trifluoromethanesulfonic acid. O-glycosyl compounds of sialic acid are prepared in high resio- and stereo-selectivity and in high yields.

Processes of preparing sialoglycosyl compounds

An oligosaccharide derivative of the formula: ##STR1## wherein R is --SR.sup.2, ##STR2## R.sup.1 is an optically detectable group, etc.; R.sup.2 is alkyl or substituted alkyl; and n is zero or 1-5, is effective as a substrate for measuring .alpha.-amylase activity and can be synthesized easily in high yield.

Oligosaccharide derivatives suitable for .alpha.-amylase determination

4,6-o-hydroxyphosphoryl-glucosamine derivatives

Lipid A monosaccharide analogues

Growing community of inventors

Gifu, Japan

Akira Hasegawa