Canon Kabushiki Kaisha

Kyowa Hakko Kogyo Co., Ltd.

Other

Nippon Zeon Company, Ltd.

Akira Asai

Shigeki Matsutani

Masayoshi Tachihara

Sadayuki Sugama

Yoshinori Yamashita

Tamio Mizukami

Hiroyuki Ishinaga

Toshio Kashino

Kiyomitsu Kudo

Hiroyuki Sugiyama

Masanori Takenouchi

Katsuhiro Shirota

Toshiharu Inui

Masashi Miyagawa

Norio Ohkuma

Yoshihisa Takizawa

Kazuhiro Nakajima

Hiromitsu Saito

Hisao Yaegashi

Eiji Kobayashi

Katsushige Gomi

Masahiro Okuda

Satoru Nagamura

Yasuyuki Tamura

Hidetoshi Suzuki

Yutaka Kanda

Tsutomu Akama

Akihiko Yamano

Shiro Akinaga

Katsuhiko Ando

Tadashi Ashizawa

Keiko Ochiai

Katsuhiko Shinjo

Toshiaki Aiba

Teruyoshi Washizawa

Noritake Suzuki

Kazuhiro Takada

Masanori Mitome

Tsutomu Agatsuma

Akira Mihara

Shingo Kakita

Katsuhiko Sinjo

Nobuhiro Yoshikawa

Masami Ikeda

Takayuki Yagi

Richard L Tolman

Hirokazu Komuro

Hiroyuki Yamaguchi

Aya Yoshihira

Tatsuo Furukawa

Hirofumi Nakano

Yasuhiro Suzuki

Keiichi Murai

Yutaka Saitoh

Yoshie Asakawa

Tsutomu Kawai

Toshiaki Sasaki

Hiroshi Handa

Shinichi Hirasawa

Hidenori Watanabe

Yoshimasa Okamura

Koichi Tanji

Mieczyslaw A Piatyszek

Shun-ichi Ikeda

Ryuichiro Nakai

Youichi Uosaki

Mamoru Tsukada

Shinji Nara

Hideki Kawasaki

Kozo Ouchi

Haruma Kawaguchi

Allison C Chin

Harumi Ogawa

Kota Nakano

Ryan Holcomb

Katsunori Kita

Atsuhiro Hasegawa

Yasuji Ohtsuka

Ritsuko Katahira

Kaori Endo

Masanori Kuroda

Daichi Tsutsumi

Upinder Singh

In an optimum design method comprising a first solution determining step of solving an optimization problem of a first evaluation function for a state variable vector with a design variable vector being as a parameter, and a second solution determining step of solving an optimization problem of a second evaluation function for the design variable vector and the state variable vector thus obtained, the second solution determining step includes the steps of computing a gradient vector of the second evaluation function for the design variable vector, computing a first coefficient based on a value of a norm of the gradient vector, computing a search vector based on the first coefficient, computing a second coefficient, and updating the design variable vector based on the second coefficient. The second coefficient computing step includes the first solution determining step, the first solution determining step is executed as an iterative method based on the gradient vector, and the state variable vector is not initialized during iteration. The optimum design method is precisely adaptable for structural changes.

Optimum design method and apparatus, and program for the same

The solution of a constrained optimization problem is easily solved by linearly approximating a point of interest to a first hypersurface given as a constraint and finding the extreme value of the objective function by moving a point r along a curved line having second-order osculation with the geodetic line of a hypersurface S(r)=c and passing through the point r.

Optimization method and optimization apparatus

A method for numerical calculation related to fluids which is efficient and less liable to cause numerical diffusion and does not rely upon the functional form of an equation of state and hence can be used as a generalized numerical calculation method. A flux is divided into an advection part, a pressure-dependent part, and a dissipation part, according to physical properties thereof, to calculate a one-dimensional basic equation. A time evolution is executed on the advection part and the pressure-dependent part using an upwind difference type leap-frog difference method and a central difference type leap-frog difference method, respectively.

Method and apparatus for numerical calculation related to fluids, program for implementing the method, and storage medium storing the program

There is provided an interpolation method for the Volume-of-Fluid (VOF) applied to a two-phase incompressible fluid, in particular, which makes it possible to cause time evolution of a shape-describing function based on the Volume-of-Fluid (VOF) method while preserving a sharpness of a shape described by the function. The method defines a function F on a one-dimensional structured grid formed on a one-dimensional real region, the function being defined through definition of a value thereof at a center of each cell within the one-dimensional structured grid, as an interpolation function H. With respect to a cell of interest on the one-dimensional structured grid, a slope is set to zero if a forward difference and a backward difference of the function f have different signs, and to a value twice as large as a smaller one of absolute values of the forward difference and the backward difference if the forward difference and the backward difference have the same sign. The function F on a partial region of the one-dimensional real region determined by the cell of interest is defined by a linear function having a value of F0 at a center of the cell of interest and the slope.

Interpolation method, apparatus for carrying out the method, and control program for implementing the method

Optimum design method, and apparatus, and program for the same

During an incompressible fluid movement, three consecutive times during the movement of the fluid are called first, second, and third times in time order, calculation is performed with two different types of lattices for the first and third times and for the second time. Momentum and mass density at the first time are temporally developed to the third time in accordance with a conservation law by using an upwind velocity field. A pressure at the second time is determined so that a velocity field derived from momenta at the third time satisfies an incompressibility condition, and the field at the third time is corrected by adding a change in momentum caused by a pressure term using the determined pressure. This prevents pressure vibration and avoids the complexity of advective term calculation.

Information processing apparatus for numerically analyzing incompressible fluid and method therefor

It provides a finite element method library which improves the reliability of a program using the finite element method as a library, and avoids calculation errors and an increase in convergence time due to programming errors. To this end, a library that describes a program process based on the finite element method is characterized in that a vector of a vector space spanned by basis functions of the finite element method, and a dual vector of a dual vector space defined by a metric derived from an inner product which is determined by the square integrations of the basis functions, are defined as different abstract data types.

Finite element method library, finite element method program, and storage medium

In a method for determining a minimum value of an optimization function under constraints given by equations, a set of points which satisfy the constraints is regarded as a Riemannian manifold within a finite-dimensional real-vector space, the Riemannian manifold is approached from an initial position within the real-vector space. An exponential map regarding a geodesic line equation with respect to a tangent vector on the Riemannian manifold ends at a finite order, an approximate geodesic line is generated as a one-dimensional orbit. An approximate parallel-translation is performed on the tangent vector on the Riemannian manifold and on the orbit generated in the orbit generating step by finite-order approximation of the exponential map regarding the parallel translation of the tangent vector. By repeating the above-described procedure from the position at which a minimum value is given until the minimum value on the orbit converges, the solution of the optimization problem with constraints is determined using a simple calculation procedure.

Optimization method with constraints and apparatus therefor

A liquid ejection head includes a liquid path; an ejection outlet forming member which constitutes a part of a wall of the liquid and which forms an ejection outlet for ejecting a droplet of liquid; a heat generating element, provided at a position opposing to the ejection outlet of the wall of the liquid flow path, for generating a bubble in the liquid by application of heat to the liquid; a restrictor portion, provided at a recessed portion of the ejection outlet, wherein the recessed portion is recessed from a plane in which the ejection outlet is formed, wherein the liquid forms a meniscus and is retained in the ejection outlet such that the restrictor portion is within the liquid, wherein an area So of an opening of the restrictor portion and a surface Sh of the heat generating element satisfy So&#x2266;Sh. According to this invention, a central portion of the meniscus opposed to the fine opening at the ejection outlet bulges, and the liquid is ejected in this state. Namely, very small amount of the liquid can be ejected, since not all of the liquid in the recess portion in the ejection outlet is ejected.

Liquid ejection head

UCS 1025 derivatives having antitumor activity or antibacterial activity which are represented by formula (I):wherein Rrepresents hydrogen, lower alkyl, etc.; Rrepresents hydrogen, or is combined with Rto represent a bond, etc., or is combined with Rto represent &#x2014;O(C&#x2550;O)&#x2014;, etc.; Rrepresents hydrogen, etc., or is combined with Rto represent a bond, etc.; Rrepresents hydrogen, etc., or is combined with Rto represent &#x2014;(C&#x2550;O)O&#x2014;, etc.; Rrepresents hydrogen or is combined with Rto represent a bond; Rrepresents hydrogen, etc., or is combined with Rto represent a bond; Rrepresents hydrogen or is combined with Rto represent &#x2550;O; Rrepresents hydroxy or is combined with Rto represent &#x2550;O;represents a single bond or a double bond, and a represents a single bond (two carbon atoms to which a is bound are combined to form a single bond) or an oxygen atom, or pharmaceutically acceptable salts thereof.

UCS1025 derivatives

A liquid discharging method comprises the step of displacing the free end of the movable member following the creation of air bubble in the air bubble generating area. For this method, the fulcrum of the movable member is positioned on the side different from liquid discharging side with respect to the displacement area for the free end of the movable member to be displaceable, and at the same time, the free end thereof is arranged to face the effective bubbling area positioned on the downstream side of the central portion of the length of the effective bubbling area that forms the bubble generating area in the direction of the movable member from the fulcrum to the free end thereof, and a part of the effective bubbling area positioned to face the free end of the movable member on the downstream side of the effective bubbling area is arranged to face the displacement area directly. Thus, the initiation of the displacement of the free end of the movable member is effectuated quickly and reliably, and the pressure exerted by the air bubble creation is led to the discharge port side and the fulcrum side of the movable member sufficiently at the time of bubbling, and the development of air bubble that follows is directed to the discharge port side more reliably and efficiently.

Liquid discharging method accompanied by the displacement of a movable member, a liquid jet head for implementing such method, and a liquid jet apparatus for the implementation thereof

An electron-beam generating device, in which a number of cold cathode elements are matrix-wired, as well as a method of driving the device, is applied to an image forming apparatus. Statistical calculations are performed in advance with regard to a required electron-beam output, and loss produced in the matrix wiring is analyzed. Drive signals are corrected by deciding optimum correction values based upon the analytical results. As a result, when rows of the matrix are driven successively row by row, the intensity of the outputted electron beams can made accurate for any driving pattern.

Electron-beam generating device having plurality of cold cathode elements, method of driving said device and image forming apparatus applying same

Thiazolidinedione compounds, compositions, and methods of inhibiting telomerase activity in vitro and treatment of telomerase mediated conditions or diseases ex vivo and in vivo are provided. The methods, compounds and compositions of the invention may be employed alone, or in combination with other pharmacologically active agents in the treatment of conditions or diseases mediated by telomerase activity, such as in the treatment of cancer. Also disclosed are novel methods for assaying or screening for inhibitors of telomerase activity.

Telomerase inhibitors and methods of their use

A liquid jet recording method includes applying thermal energy to liquid in a liquid passage to produce film boiling of the liquid to produce a. bubble; permitting the bubble to communicate with ambience; wherein the liquid passage is not blocked in the communicating step.

Recording method and apparatus for controlling ejection bubble formation

In a driving method of an ink-jet recording head, heat is generated by applying a drive signal to a heating element, and this heat is applied to ink to generate a bubble and discharge the ink through a discharge outlet. The drive signal comprises a first drive signal for storing foaming energy in the ink, and a second drive signal for generating a bubble in the ink. The second drive signal has a signal time shorter than the boundary foaming time at which foaming energy decreases in a case of performing foaming only by the second drive signal. The first drive signal is applied prior to the second drive signal in order to compensate for a decrease in foaming energy.

Driving method of ink-jet recording head, and recording apparatus for performing the driving method

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Kanagawa, Japan

Akira Asai