Hisamitsu Pharmaceutical Company, Inc.

Akio Takeuchi

Yasunori Takada

Tetsuro Tateishi

Takashi Yasukochi

Naoki Yamamoto

Satoshi Amano

Atsushi Sonobe

Hisakazu Kurita

Kenji Ishigaki

Kumi Morimoto

Takao Kurokawa

Kaori Yamaguchi

Naoto Kamakura

Makoto Suzuki

A patch comprises a backing and an adhesive layer laminated on at least one surface of the backing, in which the adhesive layer contains at least one selected from the group consisting of fentanyl and salts thereof, and contains an adhesive base material and an antioxidant having a sulfur atom in its molecule.

Patch

Provided is a medicated patch containing a medicinal agent, an adhesive base material and a tackifier, where the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material and the tackifier is a rosin-based tackifier selected from the group consisting of rosin, rosin derivatives and hydrogenated products of the foregoing, or a non-rosin-based tackifier selected from the group consisting of aliphatic hydrocarbon resins and alicyclic hydrocarbon resins, and when a non-rosin-based tackifier is added as the tackifier, a solubilizer for the medicinal agent is further added, the solubilizer containing an alcohol-based solubilizer having at least a solubility parameter of 20-35.

Medicated patch

Provided is a medicated patch containing a medicinal agent and an adhesive base material and having an acid value of no greater than 28, where the medicinal agent is varenicline or a pharmaceutically acceptable salt of varenicline.

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Tsukuba, Japan

Akio Takeuchi