Patent Technology Development Inc.

National Institute of Advanced Industrial Science and Technology

Akinori Tsuruda

Syuichi Oka

Mitsuo Suzuki

Satoshi Nakazato

Yasuhiro Kawano

It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.

Epithelial cell growth promoter

At least one substance selected from the group consisting of a water-soluble peptide comprising at least one unit selected from the group consisting of an isoleucylglycylseryl unit, a prolylisoleucylglycylseryl [SEQ ID NO: 2] unit, a glycylprolylisoleucylglycylseryl [SEQ ID NO: 6] unit, a glycylprolylisoleucylglycylthreonyl [SEQ ID NO: 7] unit, a prolylisoleucylglycyl unit and a glycylprolylisoleucylglycyl [SEQ ID NO: 1] unit and a water-soluble salt thereof can be used as an UV-induced dermatitis inhibitor or atopic dermatitis inhibitor.

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Tsukuba, Japan

Akinori Tsuruda