Canon Kabushiki Kaisha

Nec Corporation

Keio University

Akinori Hashiguchi

Michiie Sakamoto

Tsuguhide Sakata

Shinobu Masuda

Osamu Nagatsuka

Masahide Hasegawa

Koichiro Nishikawa

Akira Saito

Tsutomu Shimada

Tokiya Abe

Masahiro Ando

Hirotake Ando

Kazuhiko Kato

Maki Sano

Akihiro Sakai

Tomoharu Kiyuna

Ken Yamazaki

A microscope system comprises a microscope body, a stage configured to place a slide as an observation target and move in an X direction and a Y direction. The microscope system changes an arrangement of the placed slide with respect to the stage so as to cause a direction indicated by a mark provided on the slide placed on the stage to align with one of the X direction and the Y direction of the stage.

Microscope system, control method, and program

A microscope system includes a microscope body, a camera connected to an observation optical system of the microscope body, and an XY stage on which a slide of an observation object is placed and which is configured to move in an X-axis direction and a Y-axis direction that are orthogonal to each other. The XY stage includes an XY two-dimensional scale plate. The XY two-dimensional scale plate includes a first mark configured to provide X-axis direction axis information and Y-axis direction axis information of the stage, and a second mark which is provided within an observable region of the camera on the same plane as the first mark and which is available for recognizing a position of an XY plane of the first mark in a Z-axis direction at each of a plurality of points by focus detection of the camera.

Microscope system

A microscope system includes an observation optical system including an objective lens, an XY stage capable of moving an XY plane in an X-axis direction and an Y-axis direction, a first change unit configured to change a slant of the XY plane with respect to an optical axis direction of the objective lens, and a second change unit configured to change a slant of a slide placed on the XY stage with respect to the XY plane. Changing the slant of the XY plane by the first change unit is performed based on a first mark arranged on the XY plane at a position observable by the observation optical system. Changing the slant of the slide with respect to the XY plane by the second change unit is performed based on a second mark arranged on the slide.

Microscope system and method of controlling the same

A slide used for observation by a microscope includes a label area configured to arrange a label, a cover glass area configured to arrange an observation object and a cover glass, a position reference mark arranged in a vacant area between the label area and the cover glass area and configured to specify a reference position of the slide and an X-axis direction and a Y-axis direction that are orthogonal to each other, and focus reference marks in which a predetermined pattern is repetitively arranged along two opposing sides of four sides of a periphery of the cover glass area, the focus reference marks being configured to specify a Z-axis direction orthogonal to the X-axis direction and the Y-axis direction.

Slide, set of slide and cover glass, and microscope system

A microscope system comprises a microscope body, an imaging unit connected to the microscope body and including an image sensor for capturing a microscopic image, and an XY stage configured to place a slide and move in an X direction and a Y direction. The microscope system changes an arrangement of the image sensor with respect to the microscope body so as to cause a direction defined by a pixel arrangement of the image sensor to align with one of the X direction and the Y direction of the XY stage.

Microscope system, control method thereof, and program

A microscope system includes a microscope body, an XY stage mounted on the microscope body and including a stage configured to place a slide as an observation target and move in an X-axis direction and a Y-axis direction perpendicular to each other, and an XY two-dimensional scale plate fixed to the stage. The XY two-dimensional scale plate is provided with a first mark that provides axis information in the X-axis direction throughout a movable range of the stage in the Y-axis direction and a second mark that provides axis information in the Y-axis direction throughout a movable range of the stage in the X-axis direction, which are used to recognize X- and Y-coordinates of the stage.

A microscope system comprises a microscope body, an image sensor mounted on the microscope body, and a stage that moves in an X-axis direction and a Y-axis direction, and places a slide as an observation object. The stage includes a mark used to indicate a stage reference position. The microscope system obtains positions of the stage in the X-axis direction and the Y-axis direction, and detects the stage reference position indicated by a mark provided on the stage and a slide reference position indicated by a mark provided on a slide placed on the stage. The microscope system manages the position of the stage by coordinates based on the slide reference position if the slide reference position is detected, and manages the position of the stage by coordinates based on the stage reference position if the slide reference position is not detected.

Microscope system and control method thereof

An image acquisition unit () acquires an analysis image. The analysis image is an image in which a plurality of cell nuclei in a lesion of a target person are captured. A feature-value calculation unit () calculates the feature-value relating to the cell nuclei from the analysis image. An evaluation function acquisition unit () acquires an evaluation function from an evaluation function storage unit (). The evaluation function is a function with which prediction information is calculated based on the feature-value. The prediction information generation unit () generates prediction information relating to a target person based on a feature-value, which has been calculated from an analysis image, and an evaluation function which has been acquired by the evaluation function acquisition unit (). The prediction information is information indicating a prediction of a prognosis of a disease of the target person or a prediction of malignancy of a disease of the target person.

Disease analysis apparatus, control method, and program

A pathological diagnosis assisting apparatus according to the present invention provides the diagnosis assisting information for assisting diagnosis of tissue fibrosis from the image of the stained sample, and includes an image reading unit configured to read the image of the stained sample and an image processing unit configured to process the image. The image processing unit includes an image classification unit configured to classify the collagenous fiber and the elastic fiber, a tissue area extraction unit configured to extract a tissue area, an occupancy rate calculation unit configured to calculate the occupancy rates of the collagenous fiber and the elastic fiber in the tissue area, and a diagnosis assisting information providing unit configured to provide the diagnosis assisting information based on the calculated occupancy rates of the collagenous fiber and the elastic fiber.

Pathological diagnosis assisting apparatus, pathological diagnosis assisting method and non-transitory computer readable medium storing pathological diagnosis assisting program

A pathological diagnosis assisting apparatus according to the present invention includes an image classification unit configured to classify at least one type of a specific substance, a tissue area extraction unit configured to extract a tissue area in the image of the sample, an image dividing unit configured to divide the tissue area into a plurality of sections, a specific substance occupancy rate calculation unit configured to, calculate an occupancy rate of the at least one type of the specific substance in each of the plurality of sections, and a diagnosis assisting information providing unit configured to determine an intermediate value of the occupancy rate of the specific substance from the calculated occupancy rates of the plurality of sections and to provide the intermediate value as the diagnosis assisting information.

Growing community of inventors

Tokyo, Japan

Akinori Hashiguchi