Kao Corporation

Kanebo Cosmetics Inc.

Akinori Haratake

Takeshi Ikemoto

Kyoko Miura

Masaki Yoshida

Shunsuke Yamazaki

Hideyo Uchiwa

Aya Komiya

Syunsuke Yamazaki

Bunichi Okabe

Sachiyo Hirotsu

Junichi Matsui

Motoi Hayase

Jun Sugita

Yumiko Akazawa

Yurie Kobayashi

Mitsumasa Mitani

An antiwrinkle agent, lipolysis promoter, external composition for skin, and food and beverage composition having for an active ingredient thereof a compound represented by general formula (1): (wherein R represents a hydrogen atom or an acyl group having 2 to 20 carbon atoms)or an extract obtained from guinea ginger and/or an acylation treatment product of said extract.

Antiwrinkle agent, lipolysis promoter, external composition for skin and food and beverage composition

An antiwrinkle agent which is highly effective in alleviating wrinkles caused by the photoaging. The present invention relates to an antiwrinkle agent comprising an eugenyl glycoside.

Wrinkle-diminishing agent

The present invention provides an antiwrinkle agent and skin cosmetic composition having excellent alleviating effects on wrinkles appearing due to aging, and especially at exposed locations of skin, and a high degree of safety. The present invention relates to an antiwrinkle agent and skin cosmetic composition comprising a sclareol derivative represented by the following structural formula (1). 

Antiwrinkle agent and skin cosmetic composition

The present invention is to provide skin cosmetics and anti-wrinkle agents which are excellent in reducing effect on wrinkle caused by photoaging. Skin cosmetics and anti-wrinkle agents which comprise isosorbide represented by the following formula (1). 

Skin cosmetic and wrinkle-reducing agent

The present invention is to provide skin cosmetics and anti-wrinkle agents which are excellent in reducing effect on wrinkle caused by photoaging. Skin cosmetics and anti-wrinkle agents which comprise a sugar alcohol derivative represented by the following formula (1): (wherein n is 1 to 5, preferably n=2.).

Cosmetic composition for skin and wrinkle improver

The present invention provides a method for enhancing epidermal permeability barrier function of the aged skin, which includes the step of externally administering to the aged skin an amount of a fumaric acid diester derivative expressed by the following general formula (1) as an active ingredient wherein Rrepresents a Calkylene group; Rand Reach represents a linear or branched Calkyl group; and n is an integer of 2 to 5.

Skin external agents and drugs

Skin external agent compositions and drugs characterized by containing fumaric acid diester derivatives represented by following general formula (1), wherein Rrepresents Calkylene; Rand Rrepresent each liner or branched Calkyl; and n is an integer of 2 to 5; which provide epidermal barrier function potentiating agents and skin external agent compositions having a high safety, quickly relieving epidermal permeation barrier function failures and having an effect of maintaining the skin in a cosmetologically healthy state; agents to be used together with HB-EFG expression inducing agents accelerating epidermal turnover, amphiregulin expression inhibitors regulating excessive epidermal proliferation, and retinoic acid or its derivative preventing skin chapping caused by retinoic acid or its derivative; and skin aging relieving agents capable of ameliorating depression in the skin metabolism and thinning in association with aging.

Growing community of inventors

New York, NY, United States of America

Akinori Haratake