Kyowa Hakko Kirin Co., Limited

Akinori Hamaguchi

Michihiko Suzuki

Takeshi Kuboyama

Masahiro Matsubara

Kimihisa Ueno

Kozo Yao

Arata Yanagisawa

Seiji Aratake

Kazuki Hemmi

Yukihito Tsukumo

The present invention provides a PPAR &#x3b3; agonist comprising, as an active ingredient, a tricyclic compound represented by the formula (I) (wherein Rrepresents lower alkyl optionally having substituent(s) or the like, Rand Rare the same or different and each represents lower alkyl optionally having substituent(s) or the like, Rand Rare the same or different and each represents a hydrogen atom or the like, Q-Q-Qrepresents CH&#x2550;CH&#x2014;CH&#x2550;CH or the like, Y represents a single bond or the like, Z-Zrepresents C&#x2550;CR(wherein Rrepresents a hydrogen atom or the like), or the like, and A represents &#x2014;COOH or the like), or a pharmaceutically acceptable salt thereof and the like.

Tricyclic compounds

Growing community of inventors

Shizuoka, Japan

Akinori Hamaguchi