Ajinomoto Co., Ltd.

Akiko Okajima

Seiji Niwa

Akira Takahara

Tomoko Takeda

Yukitsugu Ono

Hajime Koganei

Seiji Ohno

Shinichi Fujita

Satoshi Iwayama

Kayo Otani

Masako Hagihara

Morikazu Kito

Yuki Kajigaya

Achiral pyrimidine derivatives and pyridine derivatives of the following formulae or analogs thereof have selective N-type calcium channel antagonistic activity and showed analgesic action when they were taken orally. They are useful as therapeutic agents for pains and various diseases associated with the N-type calcium channels. 

Pyridine compounds useful as N-type calcium channel antagonists

Achiral pyrimidine derivatives and pyridine derivatives of the following formulae or analogs thereof have selective N-type calcium channel antagonistic activity and showed analgesic action when they were taken orally. They are useful as therapeutic agents for pains and various diseases associated with the N-type calcium channels 

Pyrimidine compounds useful as N-type calcium channel antagonists

Dihydropyrimidine derivatives of the following formula or analogs thereof have selective N-type calcium channel antagonistic activity, and they are used as therapeutic agents for various diseases participating in the N-type calcium channels.

Dihydropyrimidine compounds and compositions containing the same

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Kawasaki, Japan

Akiko Okajima