Olympus Corporation

Olympus Optical Company, Ltd.

Olympus Corportion

Akihiro Kitahara

Shintaro Kobayashi

Hideo Watanabe

Yasuo Funakoshi

Kenji Tajima

Reisuke Osada

Hiroshi Miyajima

Kenichi Kusaka

Yoshitaka Kamiya

Masayoshi Karasawa

Masanori Ogata

Yusuke Amano

Hiroyasu Hebiishi

Masaru Mizunaka

Madoka Ito

Hironori Utsugi

Shuji Nakagawa

Mina Kobayashi

Shinsuke Kaneki

Yusuke Matsumoto

Tsukasa Nittono

Nobuhiro Kita

Mika Fukuda

Shuji Akiyama

Asao Uenodai

Shota Takenaga

A microscope includes: an objective lens having an optical system; a correction collar provided on the objective lens and configured to move the optical system in a direction of an optical axis of the optical system by rotating around the objective lens to correct aberration; a switching unit to which the objective lens is attachable and which switches a position of the objective lens; a supporting unit for supporting the switching unit; and a focusing unit that holds the supporting unit such that the supporting unit is movable along the optical axis of the objective lens. A correction collar operating device is detachably attached to the supporting unit and includes: an input unit for inputting rotary force to rotate the correction collar; and a correction collar driving unit for rotating the correction collar according to the rotary force while the correction collar driving unit has contact with the correction collar.

Microscope system and correction collar operating device

An inverted microscope includes: an epifluorescence illumination optical system configured to irradiate a specimen on a stage with epi-illumination light from below the stage; a transmitting illumination optical system configured to irradiate the specimen on the stage with transmitting illumination light from above the stage; an objective lens arranged below the stage and configured to collect the epi-illumination light on the specimen; and a light blocking unit configured to be arranged between the stage and the transmitting illumination optical system so as to be located on or deviated from an observation optical axis of the inverted microscope, and configured to be located at a light blocking position separated from the stage so as to block all direct light entering the objective lens at an angle not larger than an aperture angle of the objective lens.

Inverted microscope and light blocking device for inverted microscope

A microscope apparatus includes a stage and a revolver that holds objective lenses. At least one of the stage and the revolver constitutes an electric movable device that is electrically operated. The microscope apparatus further includes an input device for inputting a command for operating the electric movable device, a manual focusing device for adjusting a relative distance between the stage and the objective lenses, an operation control device for controlling operation of the electric movable device, a state determining device for determining whether the electric movable device is in an operable state or not, and a restriction device for restricting an output of a control signal for commanding the operation to the operation control device when the command for operating the electric movable device is input if the electric movable device is in an inoperable state.

Microscope apparatus having electric and manual movable devices

An inverted microscope includes an imaging lens configured to form an image of light which passes through an objective lens from a specimen, and a microscope main body in which a plurality of optical devices are configured to be arranged between the objective lens and the imaging lens in a direction of an optical axis of the objective lens and which includes therein a plurality of installation units that allow the plurality of optical devices to be fixed independently of one another. Each of the plurality of installation units includes an abutting reference surface on which any one of the plurality of optical devices is configured to be abutted. A plurality of abutting reference surfaces of the plurality of the installation units are shifted from one another in a direction perpendicular to the optical axis of the objective lens.

Inverted microscope

An inverted microscope includes: a stage which places a specimen thereon; a light source unit which has a light source irradiating light to the specimen on the stage; an objective lens which focuses at least observation light from the specimen on the stage; a body unit which holds at least the objective lens; a condenser which is provided on an optical axis of the objective lens; a condenser holding unit which holds the condenser; a condenser moving mechanism which movably supports the condenser holding unit and moves the condenser holding unit along the optical axis; a transmission mechanism which transmits power for moving the condenser to the condenser moving mechanism; and an input unit which inputs the power to the transmission mechanism. The input unit is provided above the condenser holding unit.

Inverted microscope including condenser power transmission mechanism provided in support column and illumination support portion

An inverted microscope includes: a microscope main body; a stage that is supported by the microscope main body; and an observation optical system that allows observing a sample placed on the stage from underneath, the microscope main body, in which an optical device can be attached between an objective lens and a tube lens which constitute the observation optical system including a plurality of stage supporting parts that support the stage; and a beam part that connects, in a manner of locating between the tube lens and the objective lens, at least a pair of stage supporting parts at front and back sides together among the plurality of stage supporting parts.

Microscope

A confocal microscope includes an objective lens for converging light which is emitted from a light source to a sample, a scanning mechanism for relatively scanning the sample with the light converged to the sample, and a plurality of confocal diaphragm apertures that are arranged at positions optically conjugate to the light-gathering position of the objective lens and have different diaphragm diameters. The confocal microscope further includes a plurality of photodetectors for detecting the intensities of lights respectively transmitting through the confocal diaphragm apertures, and a weighting/combining arithmetic processing unit for combining signals output from the photodetectors after weighting the signals.

Confocal microscope which weights and combines signals output from a plurality of photodetectors and calculates omnifocal brightness information for the plurality of signals

To provide a confocal microscope for obtaining an extended image by easily determining the capturing range of an observation image without being aware of the shape of a sample to be observed, the confocal microscope comprises confocal image generating unit for generating a confocal image, first counting unit for counting a first number of pixels having a predetermined brightness level or lower among the brightness levels of the pixels of the confocal image, second counting unit for counting a second number of pixels obtained by extracting only a pixel that matches a predetermined condition for the confocal image, and boundary determining unit for detecting a boundary by determining whether or not the observation surface is within the image capturing range based on the first and the second numbers of pixels.

Confocal microscope

A confocal laser scanning microscope acquires confocal images of a sample. The microscope is provided with an optical-microscope optical system which acquires non-confocal images of the sample by detecting measurement light coming from the sample. The optical-microscope optical system includes optical systems corresponding to at least two observation methods, and one of the optical systems is selected during use.

Confocal laser scanning microscope

A first amplification unit amplifies at a predetermined amplification rate an output signal from a photodetection unit for detecting an optical signal from a specimen and detecting it. An offset unit assigns offset to an output signal from the photodetection unit. A second amplification unit amplifies at an amplification rate smaller than the amplification rate of the first amplification unit an output signal from the photodetection unit assigned the offset by the offset unit. A rectification unit rectifies an output signal from the second amplification unit. An addition unit adds an output signal from the first amplification unit to an output signal from the rectification unit.

Photodetection circuit and confocal microscope that has it

A two-dimensional optical deflector includes a first deflector, which deflects a light beam about a first axis at a high speed, a second deflector, which deflects a light beam about a second axis perpendicular to the first axis at a low speed, and a fixing mechanism, which fixes the first deflector to the second deflector. The second deflector includes a rotation shaft capable of rocking about the second axis. The fixing mechanism includes a fixing member having a rotation shaft fixing hole, which engages with the rotation shaft with almost no space, and a fastener, which decreases the diameter of the rotation shaft fixing hole of the fixing member. The fixing member includes a first deflector mount surface. The first deflector is fixed to the fixing member so that a reflecting surface of the first deflector in a non-actuation state is almost parallel to the first deflector mount surface.

Two-dimensional optical deflector

In a confocal laser microscope, a confocal image and a non-confocal image of an observation target are generated from light reflected by the observation target, and the confocal image and non-confocal image are displayed side by side on the same screen.

Confocal laser microscope displaying target images side by side

An optical microscope apparatus includes an illumination optical system for illuminating an observation target object; an observation optical system for introducing an observation image of the observation target object; and an image rotation device provided on a light path common to the illumination optical system and the observation optical system, for rotating the observation image. The image rotation device is arranged so as to reflect a light beam entering thereinto, for odd-numbered times and to thereafter emit the light bean therefrom, and is driven to be rotated around an entering/exiting optical axis, thereby to rotate the observation image. The optical microscope apparatus further includes a scanning optical system provided in the illumination optical system, for deflecting observation light to be irradiated on the observation target object, within a predetermined angle range, so as to enter into the image rotation device, so that the sample is scanned with the observation light; and a control device for controlling a deflection angle of the scanning optical system, based on a rotation amount of the image rotation device, such that a scanning range of the observation light is adjusted to a substantially equal position, with respect to the observation target object, regardless of rotation operation of the image rotation device.

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Hino, Japan

Akihiro Kitahara