Fuji Photo Film Company, Limited

Astellas Pharma Gmbh

Akihiko Sasaki

Masakazu Miyazaki

Ko Tanaka

Seiji Takae

Hiroaki Atsumi

Provided is a pharmaceutical composition containing 6-ethyl-3-{3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino}-5-[(oxan-4-yl)amino]pyrazine-2-carboxamide or a pharmaceutically acceptable salt thereof and a sweetener for reducing the bitterness of gilteritinib, suppressing the decrease in dissolution stability of gilteritinib due to, for example, stress such as heat and/or humidity over time, and having excellent dissolution stability. The pharmaceutical composition contains gilteritinib or a pharmaceutically acceptable salt thereof, a sweetener, and sugars and/or sugar alcohols.

Pharmaceutical composition

A sound signal recorded in a memory synchronously with a low-frequency clock signal is read out with the low-frequency clock signal to reproduce a normal sound, thereby enabling checking of the sound signal recorded in the memory. For recording in a recording medium, the sound signal is read out with a high-frequency clock signal to effect time axis compression. By designating an address to start writing, a sound signal can be written starting with any address thereby facilitating editing. An analog sound signal previously recorded on a magnetic recording medium is time axis expanded by a time axis expansion device and then outputted from a sound output device, and the analog sound signal is hybridized with another analog sound signal inputted from a microphone, time axis compressed by a time axis conversion device, and recorded on the magnetic recording device.

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Akihiko Sasaki