Kabushiki Kaisha Tsumura Juntendo

Kabushiki Kaisha Tsmurajuntendo

Akihide Kooda

Itsuo Nishioka

Shoji Yahara

Takeshi Nishiyori

New hydroxybiphenyl compounds of the general formula: ##STR1## wherein R.sub.1 stands for a hydrogen atom or a hydroxyl group, R.sub.2 for a hydrogen atom or a hydroxyl group, R.sub.3 for a hydroxyl group, a group of the formula --CH.sub.2 --CH.dbd.CH.sub.2 or a group of the formula --CH.dbd.CH--CHO, R.sub.4 for a hydrogen atom or a group of the formula ##STR2## and R.sub.5 for a hydroxyl group or a group of the formula ##STR3## These compounds are obtained by extraction of 'Tokoboku', i.e. dried cortex of Magnolia officinalis which belongs to the family Magnoliaceae. They are useful as pharmaceuticals or intermediates therefor, in particular as anti-allergics.

Anti-allergic hydroxybiphenyl compounds

New hydroxybiphenyl compounds of the general formula: ##STR1## wherein R.sub.1 stands for a hydrogen atom or a hydroxyl group, R.sub.2 for a hydrogen atom or a hydroxyl group, R.sub.3 for a hydroxyl group, a group of the formula -CH.sub.2 -CH.dbd.CH.sub.2 or a group of the formula -CH.dbd.CH-CHO, R.sub.4 for a hydrogen atom or a group of the formula ##STR2## and R.sub.5 for a hydroxyl group or a group of the formula ##STR3## These compounds are obtained by extraction of 'Tokoboku', i.e. dried cortex of Magnolia officinalis which belongs to the family Magnoliaceae. They are useful as pharmaceuticals or intermediates therefor, in particular as anti-allergics.

Growing community of inventors

Gifu, Japan

Akihide Kooda