Senju Pharmaceutical Co., Ltd.

Kakuji Tojo

Akiharu Isowaki

Akira Ohtori

Tomoko Nakajima

Kohji; c/o Nichiban Co Ltd Kawahara

Akira; Ohtori

Yasuhiko; c/o Nichiban Co Ltd Aramomi

The present invention provides a percutaneously absorptive preparation for preventing or treating allergic eye disease, which comprises olopatadine or a salt thereof as an active ingredient. In addition, the present invention provides a method for preventing or treating allergic eye disease, which comprises applying a percutaneously absorptive preparation comprising olopatadine or a salt thereof to the skin surface including the skin surface of an eyelid, thereby casing transfer of a therapeutically effective amount of olopatadine or a salt thereof from the preparation to an anterior ocular segment through the skin of the eyelid rather than a systemic blood flow. The present preparation can exert a pharmacological effect over a prolonged period by a single application, as compared to conventional preparations such as eye drops.

Percutaneously absorptive ophthalmic preparation comprising olopatadine

Ophthalmic adhesive preparations for percutaneous absorption to be used in treating diseases in the posterior parts of eye characterized by having a drug-containing layer which contains a drug to be delivered to the posterior parts of eye including the crystalline lens, the vitreous body, the uvea and the retina, together with a percutaneous sorbefacient comprising polyoxyethylene oleyl ether and/or isopropyl myristate uniformly dispersed in a base matrix.

Ophthalmic adhesive preparations for percutaneous adsorption

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Akashi, Japan

Akiharu Isowaki