Council of Scientific & Industrial Research

Reliance Industries Limited

Ajay Kumar

Ram Asrey Vishwakarma

Sandip Bibishan Bharate

Sonali Sandip Bharate

Raksh Vir Jasra

Nagesh Sharma

Prashant Joshi

Veera Venkata Satya Bhaskara Sita Rama Murthy Katravulapalli

Anilkumar Mettu

Mehak Gupta

Kalpana Gopalakrishnan

Vikas Kumar

Paramvir Singh Ahuja

Amit A Bhattacharya

Indra Sandal

Ashu Gulati

Rohit Singh

Ravindranath Srigiripuram Desikalhar

Kalpana Gopalakrishna

Abubakar Wani

Sudhakar Manda

Sumit Gandhi

Naresh Kumar Satti

Ajit Kumar Saxena

Madhukar Onkarnath Garg

Inshad Ali Khan

Dilip Manikrao Mondhe

Girish Badrinath Mahajan

Ashok Kumar

Shashi Bhushan

Shrikant Madhusudan Nanoti

Santosh Kumar Guru

Aashiq Hussain

Asif Khurshid Qazi

Sunil Agrahari

Parduman Sharma

Rohit Sharma

Suresh Kumar

Pralay Das

Ashok Manikrao Biradar

Sanat Kumar

Rakha Hari Das

Samsher Singh

Ramesh Mudududdla

Gananath Doulat Thakre

Bikarma Singh

Shaifali

Anil Kumar Katare

Meghpati Singh

Sarita Rani

Abid Hamid

Anu Malik

Chudasama Chintansinh Dharmendrasinh

Sachin Rawalekar

Katravulapalli Veera Venkata Satya Bhaskara Sita Rama Murthy

Sadhana Sharma

Jaideep Bharate

Baljinder Singh

Zahoor Wani

Hayat Ullah Khan

Manisha Sahai

Savita Kaul

Bal Mukand Shukla

Paulose Anthony Thrissokaran

Ajit Kumar Chaturvedi

Prakash Jai

Amit Choudhary

Indrani Coondoo

Veera Venkata Katravulapalli

Naresh Satti

The present invention relates to the novel formulation for sustained or delayed release of rohitukine-richextract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract/fraction of rohitukine-richwith polymers has resulted in a sustained release of the extract or fraction over a period of 16-24 hrs. The said formulations are useful in the treatment of inflammatory diseases.

Sustained release formulations of

The present invention is related to the novel oral dosage form for sustained release of crocin-1, a active constituent ofextract or fraction and a process for preparing the same wherein the extract is wet-granulated using excipients, biodegradable polymers and/or non-biodegradable polymers alone or in combination. The said formulations are useful for the treatment of chronic inflammatory diseases wherein NLRP3 inflammasome is involved.

Sustained release formulations of dysoxylum binefacterum

The present invention is related to a novel gastroretentive swellable oral dosage form for sustained or delayed release of bergenin, a active constituent ofextract/fraction and a process for preparing the same wherein the extract is wet-granulated using excipients i.e. biodegradable polymers and/or non-biodegradable polymers alone or in combination, and the said granules are either filled into a capsule or compressed into a tablet. The said formulation comprising a granulated extract of bergenin-richwith polymers has resulted in a sustained release of extract in the stomach over a period of 16-24 hrs. The said formulations are useful for the treatment of inflammatory diseases.

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The present invention relates to a new protocol for 'Process development for 5-hydroxymethylfurfural (5-HMF) synthesis from carbohydrates'. A convenient, atom-economic, highly selective and cost-effective process has been developed for the preparation of 5-HMF from cellulose, hemicellulose, starch, different sources of carbohydrates and further extended to glucose and fructose.

Process development for 5-hydroxymethylfurfural (5-HMF) synthesis from carbohydrates

The present disclosure relates to a reforming catalyst and a process for preparing the same. The acidic functionality of the catalyst is suppressed by using a chloride free alumina and coating the chloride free alumina with Group V B metal oxide in the catalyst, which helps in minimizing the cracking reactions and achieving higher selectivity for liquid hydrocarbons and aromatic hydrocarbons.

Reforming catalyst and a process for preparation thereof

The present disclosure relates to a reforming catalyst composition comprising a spherical gamma AIOsupport; at least one Group VB metal oxide sheet coated on to the AIOsupport; and at least one active metal and at least one promoter metal impregnated on the AIOcoated support. The reforming catalyst composition of the present disclosure has improved activity, better selectivity for total aromatics during naphtha reforming and results in less coke formation. The reforming catalyst composition has improved catalyst performance with simultaneous modification of acidic sites as well as metallic sites through metal support interaction. The acid site cracking activity of the catalyst is inhibited because of the use of chloride free alumina support modified with solid acid such as Group VB metal oxide and impregnated with active metals. The present disclosure provides a process for naphtha reforming in the presence of the reforming catalyst composition of the present disclosure to obtain reformates of naphtha.

Reforming catalyst and a method of preparation thereof

A process and system for modifying heterogeneous catalysts by contacting them with chemical compounds to functionalize the surface of the heterogeneous catalyst. A polymetallic catalyst including bimetallic catalyst is functionalized on its surface by employing a precursor of an inorganic compound. The precursor of the inorganic compound is an organometallic compound, and the metal based inorganic compound is aluminum oxide. A process and system for surface modification functionalization of the heterogeneous catalysts at conditions including room temperature and atmospheric pressure.

Modified heterogeneous catalyst

The present invention relates to the alkylidene phosphonate esters of formula I wherein, Ris selected from a group consisting of hydrogen or alkyl group; Ris selected from a group consisting of hydrogen, hydroxy, alkyl, alkoxy, nitro, halogen, amino, N-substituted alkylamino; alkyl group is selected from a group consisting of methyl, ethyl and isopropyl; Ar is selected from a group consisting of aryl, substituted aryl, fused aryl, heteroaryl, and substituted heteroaryl. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the alkylidene phosphonate esters. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease. 

Alkylidene phosphonate esters as p-glycoprotein inducers

The present disclosure relates to a process for preparing a catalyst. The process comprises coating zeolite gel over the alumina support to obtain a chloride free zeolite gel coated alumina support, crystallizing the chloride free zeolite gel coated alumina support, washing, drying and calcining the crystallized zeolite coated alumina support to obtain a calcined crystallized chloride free zeolite coated alumina support, treating the calcined crystallized chloride free zeolite coated alumina support with ammonium nitrate to obtain sodium free support, washing, drying, and calcining the support to obtain a calcined chloride free zeolite coated alumina support, immersing the calcined chloride free zeolite coated alumina support in an active metal and a promoter metal solution mixture followed by stirring to obtain a metal coated chloride free zeolite coated alumina support, and drying and calcining the metal coated chloride free zeolite coated alumina support to obtain the catalyst.

Process for preparing a catalyst

The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl-polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimer's disease using compounds of the invention are also provided.

Polyprenylated phloroglucinol compounds as potent P-glycoprotein inducers

The present invention relates to the N-substituted beta-carbolinium compounds of general formula A and formulae I and II wherein, Rand Rgroups are selected from halogens or trifluoromethyl; Rgroup is selected from hydrogen or methyl; Ar is selected from aryl and heteroaryl, X is selected from halogens; and Rand Rgroups may be attached to any position on ring E. The present invention particularly relates to synthesis and p-glycoprotein induction activity of the N-substituted beta-carbolinium compounds. In addition, the invention relates to methods of using compounds for treating or preventing Alzheimer's disease. 

N-substituted beta-carbolinium compounds as potent P-glycoprotein inducers

A pharmaceutical composition for the treatment of multi-drug resistant infections includes an antimicrobial agent in combination the benzopyrano[3,4-b][1]benzopyran-12(6H)-one class of compound boeravinone B of Formula 1: The bio-efficacy of anti-infective drugs can be potentiated, when used in combination with boeravinone B. Boeravinone B can overcome the resistance or multi-drug resistance developed by bacteria against quinolone, mupirocin and macrolide class of anti-bacterial agents via inhibition of bacterial efflux pumps. Thus, the compositions can be used to treat or prevent drug-resistant bacterial diseases.

Pharmaceutical composition for the treatment of multi-drug resistant infections

The present invention relates to the compounds of formula I wherein R is as herein described. The present invention particularly relates to synthesis and antiproliferative activity of 10-substituted colchicinoids. Compounds of the invention can be used for prevention or in the treatment of cancer disease. 

10-substituted colchicinoids as potent anticancer agents

The present disclosure relates to a naphtha reforming process for obtaining reformed naphtha comprising contacting naphtha with a catalyst, the catalyst comprising a chloride free zeolite coated alumina support impregnated with 0.01 wt % to 0.5 wt % active metal and 0.01 wt % to 0.5 wt % promoter metal, wherein the thickness of the zeolite coating on the alumina support ranges from 100 &#x3bc;m to 200 &#x3bc;m, which results in formation of reformed products of naphtha and ethylbenzene formed in-situ.

Naphtha reforming process

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Jammu, India

Ajay Kumar