Xoma Technology Ltd.

Ajay J Narasimha

Toshihiko Takeuchi

Daniel H Bedinger

Amer M Mirza

Shireen S Khan

Daniel Bedinger

Amer Mirza

The present disclosure relates, in general, to materials and methods for antibodies specific for transforming growth factor beta (TGFβ), including TGFβ1, TGFβ2 and TGFβ3, and uses of these antibodies in the treatment of subjects having cancer, an eye disease, condition or disorder, fibrosis, including ophthalmic fibrosis or fibrosis of the eye, and other conditions or disorders related to TGFβ expression.

Antibodies that bind transforming growth factor beta (TGF beta) and methods of use thereof for treatment

The present disclosure relates, in general, to materials and methods for antibodies specific for transforming growth factor beta (TGF&#x3b2;), including TGF&#x3b2;1, TGF&#x3b2;2 and TGF&#x3b2;3, and uses of these antibodies in the treatment of subjects having cancer, an eye disease, condition or disorder, fibrosis, including ophthalmic fibrosis or fibrosis of the eye, and other conditions or disorders related to TGF&#x3b2; expression.

Method of treating cancer by administering an antibody that binds transforming growth factor beta (TGF-beta) 1, TGF-beta 2 and TGF-beta 3

Nucleic acids encoding, and methods of producing, antibodies specific for transforming growth factor (TGF)-&#x3b2;

TGF-beta-specific antibodies and methods of use thereof for treatment

Antibodies specific for TGF-&#x3b2;  and methods of treatment thereof

Antibodies specific for TGF-beta and methods for treating thereof

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San Francisco, CA, United States of America

Ajay J Narasimha