Amo Groningen B.v.

Aixa Alarcon Heredia

Carmen Canovas Vidal

Robert Rosen

Hendrik Albert Weeber

Patricia Ann Piers

Franck Emmanuel Gounou

Mihai State

Marrie H Van Der Mooren

Robert Rosén

Sieger Meijer

Dora Sellitri

Miguel Faria Ribeiro

Robin Zonneveld

Bram Koopman

Theophilus Bogaert

Luuk Franssen

Henk A Weeber

Mark Jenkins Sanchez

Jacolien Graver

Selma Boersma

John Van Den Berg

Bart Cannegieter

Hendrik A Weeber

Robert ROSÉN

Vidal Carmen Canovas

Intraocular lenses for reducing negative dysphotpsia (ND) are described herein. An example ophthalmic lens can include an optic () with a central optical zone () disposed about the optical axis (OA) and an attenuation optical zone () disposed about the central optical zone (), wherein the attenuation optical zone () is contiguous with the central optical zone (), and wherein optical power of the ophthalmic lens is gradually reduced within the attenuation optical zone ().

Intraocular lenses for reducing negative dysphotopsia

A ring halometer system configured to quantify dysphotopsias in a patient. The system includes a white screen and a first light source configured to emit a glare source from the white screen. The glare source is configured to form a veil of light visible to the patient when the glare source interacts with an optical surface of the eye of the patient. The system also includes a second light source configured to project a light ring with varying luminance concentric with the glare light source on the white screen, and a controller coupled to the second light source configured to adjust a size of the light ring. The system may also include an electronic device configured to determine a level of bothersomeness of the dysphotopsias experienced by the patient based on the size of the light ring.

Ring halometer system and method for quantifying dysphotopsias

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon.

Systems and methods for correcting photic phenomenon from an intraocular lens and using refractive index writing

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes vergence matching for an intraocular lens (IOL) having an optical profile induced by refractive index writing.

Systems and methods for vergence matching with an optical profile and using refractive index writing

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining a deviation in position of at least one optical element from a reference line corresponding to alignment of the apex of the cornea, center of the pupil, center of the IOL, and fovea, and/or determining a tilt of at least one of the optical elements relative to the reference line. The method can further include applying a plurality of focused laser pulses to a selected area of the implanted IOL to produce, through refractive index writing, a phase change pattern on the IOL that is configured to compensate for the deviation(s) and/or tilt to improve the foveal vision of the subject.

Systems and methods for improving vision from an intraocular lens in an incorrect position and using refractive index writing

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

Systems and methods for treating ocular disease with an intraocular lens and refractive index writing

Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

Progressive power intraocular lens, and methods of use and manufacture

Apparatuses, systems, and methods for providing improved intraocular lenses (IOLs) and other refractive treatment modalities involve fabricating the IOL or developing the treatment based on a refractive profile. Exemplary techniques include obtaining a base wavefront power profile corresponding to a theoretical lens, adding a second wavefront profile defined by the combination of one or more zones described by a cosine function to obtain a final wavefront power profile, determining a refractive profile based on the final wavefront power profile, and fabricating the intraocular lens or determining the treatment based on the refractive profile.

Refractive extended depth of focus intraocular lens, and methods of use and manufacture

Systems and methods for evaluating ND are described herein. An example method can include constructing a non-sequential (NSC) ray-tracing model of an eye with an ophthalmic lens, and modelling a light source and a detector. The detector can be configured to mimic a retina of the eye. The method can also include computing irradiance data using the light source, the NSC ray-tracing model, and the detector. Irradiance data can be computed for each of a plurality of pupil sizes. The method can further include evaluating ND by analyzing the respective irradiance data for each of the pupil sizes. Also described herein are methods for designing an ophthalmic lens edge that reduces the incidence of ND for a given ophthalmic lens by adjusting the edge thickness and/or the scatter.

Systems and methods for evaluating and reducing negative dysphotopsia

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one modification to be made to an IOL implanted in a subject to improve the vision of the subject, wherein the IOL has a first index of refraction; and based on the determination, applying laser radiation to at least one selected area of the IOL to form, within the IOL, at least one additional layer having a different index of refraction than the first index of refraction and a particular shape within the IOL configured to improve the vision of the subject.

Systems and methods for multiple layer intraocular lens and using refractive index writing

Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method for vergence matching includes calculating vergence of a wave after refraction on a surface of an IOL and, based on an estimated curvature, converting an initial phase map into a vergence-matched phase map, such that the initial phase map follows the curved vergence of the wavefront.

Systems and methods for vergence matching of an intraocular lens with refractive index writing

Lenses and methods are provided for improving peripheral and/or central vision for patients who suffer from certain retinal conditions that reduce central vision or patients who have undergone cataract surgery. The lens is configured to improve vision by having an optic configured to focus light incident along a direction parallel to an optical axis at the fovea in order to produce a functional foveal image. The optic is configured to focus light incident on the patient's eye at an oblique angle with respect to the optical axis at a peripheral retinal location disposed at a distance from the fovea, the peripheral retinal location having an eccentricity between &#x2212;30 degrees and 30 degrees. The image quality at the peripheral retinal location is improved by reducing at least one optical aberration at the peripheral retinal location. The method for improving vision utilizes ocular measurements to iteratively adjust the shape factor of the lens to reduce peripheral refractive errors.

Intraocular lenses that improve peripheral vision

A multi-piece IOL assembly is provided that includes a platform and an optic. The platform has an inner periphery surrounding an inner zone of the platform. The optic has an optical zone, an outer periphery and a retention mechanism disposed on the outer periphery. The optic is configured to be disposed in the inner zone of the platform and to extend to a location between the inner periphery and the outer periphery of the platform to be secured to the platform at the location. The platform can be secured to an inner periphery of the eye or can be formed into a natural lens by cutting the lens using a laser or other energy source.

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Groningen, Netherlands

Aixa Alarcon Heredia