Medical University of South Carolina

Aidaris Jimenez

Jian Zhang

Michael Matthews

Methods for sterilizing a biocompatible hydrogel polymer are provided via treating the biocompatible hydrogel polymer with a supercritical COtreatment composition at a treatment pressure of about 4 MPa to about 30 MPa and a treatment temperature of about 5&#xb0; C. to about 75&#xb0; C. The supercritical COtreatment composition can be substantially pure COor may further include hydrogen peroxide (e.g., in an amount of about 10 ppm to about 1,000 ppm). In certain embodiments, the biocompatible hydrogel polymer can be treated with the supercritical COtreatment composition for about 30 minutes to about 5 hours. According to these methods, treating the biocompatible hydrogel polymer can kill about 90% or more of anyandpresent in the biocompatible hydrogel polymer.

Growing community of inventors

Hamilton, OH, United States of America

Aidaris Jimenez