University of British Columbia

Qlt Phototherapeutics, Inc.

Quadra Logic Technologies, Inc.

Qlt Inc.

Agnes How-Ching Chan

Julia G Levy

David W Hunt

Anna M Richter

Guillermo O Simkin

Modestus O Obochi

Simon Leong

Martin Renke

Janice North

David William Carey Hunt

Multiple sclerosis and rheumatoid arthritis can be treated effectively using photodynamic therapy. In this protocol, a photoactive compound is administered, allowed to distribute in the effected subject, and the subject is then irradiated to activate the photoactive compound. Alternatively, the blood of a subject to be treated can be subjected to PDT extracorporeally. In the case of rheumatoid arthritis, localized treatment at the joints may also be employed.

Photodynamic therapy in selective cell inactivation in blood and treating immune dysfunction diseases

Green porphyrins act as antigen-specific immunomodulators in the active phase of an immune response to a particular antigen. This effect occurs at ambient light levels.

Green porphyrins as immunomodulators

Green porphyrins act as antigen-specific immunomodulators in the active phase of an immune response to a particular antigen, as well as to interfere with intercellular communication. These effects occur in the absence of radiation absorbed by the green porphyrin.

Method for selectively reducing activated leukocyte cell population

Growing community of inventors

Port Moody, Canada

Agnes How-Ching Chan