Boston Scientific Scimed, Inc.

Greatbatch Ltd.

Boston Scientific Corporation

Afsar Ali

Thomas J Holman

Scott Schewe

Jeffrey S Lindquist

James Lee Shippy, Iii

Richard Dunn

Ken Xiao Kang Zhang

Kevin Silberg

David Parsons

Nam H Hoang

Jan Weber

Biswa P Das

Daniel James Horn

Keith W Seitz

Thomas Marzano

Robert S Rubino

Ashish Shah

Holly Noelle Moschiano

Peter G Edelman

Gary Freitag

Steven Paul Mertens

Xiaohong Tang

Brian P Hohl

Richard A Noddin

Tom Holman

Ho-Chul Yun

Leo M Klisch

David Dianetti

Todd C Sutay

Rommy U Huleis

Stacie Depner

Sourabh Biswas

Scott R Schewe

Jan Seppala

James Lee Iii Shippy

A miniature electrochemical cell having a total volume that is less than 0.5 cc is described. The cell casing is formed by joining two ceramic casing halves together. One or both casing halves are machined from ceramic to provide a recess that is sized and shaped to contain the electrode assembly. The opposite polarity terminals are metal feedthroughs, such as of gold, and are formed by brazing gold into openings machined into one or both of ceramic casing halves. A thin film metallization, such as of titanium, contacts an edge periphery of each ceramic casing half. The first ceramic casing half is moved into registry with the second ceramic casing half so that the first and second ring-shaped metallizations contact each other. Then, a laser welds through one of the casing halves being a substantially transparent ceramic, for example sapphire, to braze the first and second ring-shaped metallizations to each other to thereby join the first and second casing halves together to form a casing housing the electrode assembly. A solid electrolyte (LiPON) activates the electrode assembly.

Hermetic weld for a thin film electrochemical cell activated with a solid electrolyte and housed in a ceramic casing

In various examples, a feedthrough seal apparatus is configured to seal an opening in a device. The device includes a case surrounding an interior space, the case including the opening therein to allow access to the interior space from an exterior of the case. The feedthrough seal apparatus includes a plug disposed within the opening of the case. The plug is formed from at least one of a polymeric material and an adhesive material. The lead wire extends through the plug, such that a first end of the lead wire is disposed within the interior space of the case and a second end extends from the plug to the exterior of the case. The plug is configured to electrically insulate the lead wire from the case. Some examples include a method of making the feedthrough seal apparatus.

Feedthrough seal apparatus, system, and method

This disclosure relates to medical devices and related methods. In some embodiments, the methods include applying a material to the balloon and then removing the material from one or more regions of the balloon.

Medical devices and related methods

Intravascular medical devices comprising a coating layer disposed on a substrate associated with the medical device, wherein the coating layer has a pre-determined fragmentation pattern. At least a portion of the coating layer comprises a plurality of discontinuous bioresorbable members, wherein the discontinuous bioresorbable members have a size less than the luminal diameter of an arteriole. The coating layer may be formed by excavating portions of a coating layer (e.g., by laser ablation) to create gaps which define the discontinuous bioresorbable members. In certain embodiments, the coating layer is formed of a heat-bondable material. In such embodiments, the discontinuous bioresorbable members may be adhered to the substrate via heat bonds. Also disclosed are methods of forming a coating layer on medical devices and methods of treating intravascular sites.

Medical devices having a bioresorbable coating layer with a pre-determined pattern for fragmentation

Medical balloons are energetically treated to form regions that facilitate deflation to a desirable configuration.

Medical balloon deflation

A catheter assembly comprises at least one catheter shaft and a balloon. The catheter shaft comprises a substantially cylindrical portion and at least one tapered portion. The tapered portion forms an angle with the cylindrical portion of about 1 degree to about 25 degrees. At least one of the waists of the balloon is sealingly engaged to the tapered portion.

Catheter assembly with tapered joints and method of manufacture

Endoprosthesis assemblies and methods of making endoprosthesis assemblies are disclosed. For example, endoprosthesis assemblies are described that include an endoprosthesis body and a polymeric coating about the endoprosthesis body. The polymeric coatings are engaged tightly to the endoprosthesis wall through engageable features created on the surface of the polymeric coatings and the surface of the endoprosthesis wall prior to engaging the surfaces.

Endoprostheses

Catheters, balloons, and methods of manufacturing balloons for balloon catheters using lasers are disclosed. A catheter with a shaft sized for use with a 0.014 inch guide wire includes a polymeric balloon having a body portion with an inflated outer diameter of more than 6 millimeters. An inflatable balloon includes an inflated outer diameter to inner waist diameter ratio of 12.5 to 1. An inflatable polymeric balloon that has a body portion with two regions that have different molecular orientations is also provided. A method of processing an elongate polymeric material includes heating a portion of the polymeric material with a laser while longitudinally stretching the portion of the polymeric material. A method of manufacturing a balloon includes heating and longitudinally stretching a first and second portion of an elongate polymeric tube to form first and second end portion. The remaining body portion is radially expanded to form the balloon.

Balloon catheters and methods for manufacturing balloons for balloon catheters

Medical device balloons are formed from a tubular parison by a process or apparatus which establishes a controlled location (initiation zone) on the parison where radial expansion is initiated. Initiation within the initiation zone is achieved by heating the parison in that location to a higher temperature than the remainder of the parison for at least a portion of the blowing time. A variety of apparatus configurations are provided, some of which allow for the size and location of the initiation zone to be readily reconfigured. Balloons can also be modified, post-blowing, using heating apparatus and methods described.

Process for forming medical device balloons

Apparatus for forming medical device balloons

Methods of making medical devices are disclosed. In some embodiments, a method for welding together two components is described. The two components are non-coaxial and contact one another. A fixture holds the two components in a desired configuration. Electromagnetic radiation is directed at an area where the two components are in contact. The radiation causes the two portions to fuse together. The fixture has an open area or a transmissive material in the path of the electromagnetic radiation so that at least a portion of the radiation impinged up on the two components.

Methods of making medical devices

An apparatus for tacking a multi-lumen tubular assembly together comprises a laser, an optical member and a placement tray for retaining the tubular assembly. A portion of the optical member defines a window that is substantially transparent to laser energy emitted from the laser. The window has a substantially concave shaped surface. The placement tray and the window surface define a processing area for positioning at least a portion of the tubular assembly. The processing area receives the laser energy that is emitted from the laser and passed through the window of the optical member. The tubular assembly is defined by an outer tubular member disposed about at least a portion of at least one inner tubular member. The laser energy transmitted into the processing area is transmitted substantially through the outer tubular member and is substantially absorbed by at least one region of the least one inner tubular member.

Tacking method and apparatus

Process and apparatus for forming medical device balloons

Growing community of inventors

Maple Grove, MN, United States of America

Afsar Ali