Visby Medical, Inc.

Adrienne C Lam

Jesus Ching

Victor Briones

Gregory Loney

David Swenson

Adam De La Zerda

Keith Edward Moravick

Colin Kelly

Brian Ciopyk

Boris Andreyev

Helen Huang

Jonathan Hong

Valeria Revilla

Shaunak Roy

Ryan Cena

Phoebe Cao

Danielle McSheery

Jennifer Albrecht

Edward Biba

Rajinder K Bhatia

Disclosed herein are methods and devices for preparing a sample of nucleic acid molecules from a biological sample. The methods and devices may perform similarly to or better than standard sample preparation methods. The nucleic acid molecules prepared using the methods and devices provided herein may be utilized for downstream applications, including polymerase chain reaction (PCR).

Devices and methods for nucleic acid extraction

A method includes conveying a detection solution containing a target amplicon into a detection module of a molecular diagnostic test device. The detection module includes a detection surface including a series of capture probes to which a first portion of the target amplicon is bound when the detection solution is conveyed. A first reagent formulated to produce a visible signal indicating a presence of the target amplicon is then conveyed into the detection module. The first reagent is bound to a second portion of the target amplicon when the first reagent is conveyed. A second reagent is conveyed into the detection module. The second reagent includes a precipitating substrate formulated to catalyze the production of the visible signal by producing an insoluble colored product when the second reagent is in contact with the first reagent. The method includes viewing the visible signal via a transparent portion of the detection module.

Devices and methods for the detection of molecules using a flow cell

Growing community of inventors

Fremont, CA, United States of America

Adrienne C Lam